Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2401295 | 0.97 | — | — | |
| SCHEMBL6767920 | 0.82 | KDM4E (0.59) | KDM4EBBOX1TP53LMNAKMT2A | |
| SCHEMBL9936384 | 0.78 | KDM4E (0.55) | KDM4EBBOX1TP53LMNAKMT2A | |
| SCHEMBL2400137 | 0.77 | LMNA (0.50) | KDM4EBBOX1TP53LMNAKMT2A | |
| SCHEMBL7166850 | 0.77 | BBOX1 (0.56) | KDM4EBBOX1TP53LMNAKMT2A | |
| SCHEMBL384883 | 0.77 | BBOX1 (0.56) | KDM4EBBOX1TP53LMNAKMT2A | |
| SCHEMBL4588375 | 0.77 | — | — | |
| SCHEMBL222638 | 0.74 | KDM4E (0.52) | KDM4EBBOX1TP53LMNAKMT2A | |
| SCHEMBL3043744 | 0.74 | LMNA (0.57) | KDM4EBBOX1TP53LMNAKMT2A | |
| SCHEMBL3037609 | 0.74 | LMNA (0.57) | KDM4EBBOX1TP53LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | ADAMS JERRY L | 2006-10-26 | — | — | US | disclosed |
| EP-0106284-B1 | 3-ARYL-7-CHLORO-3,4-DIHYDRO-ACRIDINE-1,9-(2H,10H)-DIONE-1-OXIMES AND 1-HYDRAZONES, THEIR SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM, AND THEIR APPLICATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-06-16 | — | — | EP | disclosed |
| EP-0106284-A1 | 3-Aryl-7-chloro-3,4-dihydro-acridine-1,9-(2H,10H)-dione-1-oximes and 1-hydrazones, their salts, process for their preparation and pharmaceutical preparations containing them, and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | CHKB, MAP3K20, MAP3K6 | KDM4E 2777/4885BBOX1 558/4885TP53 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.