Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713155 | 0.70 | HTR2A (0.59) | LMNAESR1ADRA2AADORA3TACR2 | |
| SCHEMBL380602 | 0.69 | ALDH1A1 (0.57) | LMNAMEN1MAPTHPGDKMT2A | |
| SCHEMBL11867460 | 0.69 | GNAI3 (0.43) | ALDH1A1 | |
| SCHEMBL6820400 | 0.69 | HTR2A (0.62) | LMNAESR1ADRA2AADORA3TACR2 | |
| SCHEMBL11675017 | 0.69 | HTR2A (0.62) | LMNAESR1ADRA2AADORA3TACR2 | |
| SCHEMBL27030686 | 0.69 | HTR2A (0.62) | LMNAESR1ADRA2AADORA3TACR2 | |
| SCHEMBL181089 | 0.69 | ESR1 (0.73) | LMNAESR1ADRA2AADORA3TACR2 | |
| SCHEMBL10568240 | 0.69 | ESR1 (0.73) | LMNAESR1ADRA2AADORA3TACR2 | |
| SCHEMBL5831370 | 0.68 | GNAI3 (0.46) | ALDH1A1 | |
| SCHEMBL60134 | 0.68 | ESR1 (0.61) | LMNAESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006106311-A2 | COMBINATION TREATMENT METHODS FOR TREATING SEX-HORMONE DEPENDENT DISEASE AND FERTILITY TREATMENT | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2006-10-12 | — | — | WO | claimed |