Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6072863 | 0.90 | HPD (0.50) | HPDALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL997304 | 0.84 | ALDH1A1 (0.49) | HPDALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL31492417 | 0.83 | ALDH1A1 (0.52) | HPDALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL14334237 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APKMMAPT | |
| SCHEMBL2566726 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KMT2ACYP3A4PKMMAPT | |
| SCHEMBL7035878 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL25450873 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APKMMAPT | |
| SCHEMBL4715558 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APKMMAPT | |
| SCHEMBL997302 | 0.79 | ALDH1A1 (0.59) | HPDALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL8814509 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006032987-A1 | INDOLINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF ARTERIOSCLEROSIS | PFIZER PRODUCTS INC. (US) | 2006-03-30 | — | — | WO | disclosed |