Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.49 |
| ▸ | PPARG | P37231 | 8/20 | 0.49 |
| ▸ | LTA4H | P09960 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073008 | 0.94 | PPARG (0.47) | PPARAPPARGLTA4HCYP3A4RXRA | |
| SCHEMBL6073133 | 0.94 | PPARG (0.49) | PPARAPPARGLTA4HCYP3A4RXRA | |
| SCHEMBL6073140 | 0.93 | PPARG (0.43) | PPARAPPARGLTA4HCYP3A4RXRA | |
| SCHEMBL6073074 | 0.92 | PPARA (0.46) | PPARAPPARGLMNATSHRMAPK1 | |
| SCHEMBL6073240 | 0.91 | TDP1 (0.43) | PPARAPPARGLTA4HCYP3A4RXRA | |
| SCHEMBL6073141 | 0.91 | PPARA (0.56) | PPARAPPARGCYP3A4RXRANPC1 | |
| SCHEMBL6073124 | 0.89 | PPARG (0.44) | PPARAPPARGLTA4HCYP3A4RXRA | |
| SCHEMBL6073155 | 0.89 | PPARG (0.50) | PPARGLTA4HCYP3A4RXRANPC1 | |
| SCHEMBL6072990 | 0.89 | SLC2A1 (0.48) | PPARAPPARGLMNATSHRMAPK1 | |
| SCHEMBL6073210 | 0.89 | PPARG (0.50) | PPARAPPARGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | claimed |
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |