SCHEMBL6072990

SCHEMBL6072990

CCOC(=O)CN(Cc1cccc(OCCc2ccc(CC)cn2)c1)C(=O)Oc1ccc(OC)cc1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 7/20 0.48
SLC2A4 P14672 3/20 0.47
LMNA P02545 1/20 0.46
SLC2A8 Q9NY64 1/20 0.46
PPARA Q07869 9/20 0.45
PPARG P37231 9/20 0.45
CYP2C9 P11712 3/20 0.45
KCNH2 Q12809 3/20 0.45
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6073210 0.95 PPARG (0.50) SLC2A1SLC2A4LMNAPPARAPPARG
SCHEMBL6073074 0.95 PPARA (0.46) SLC2A1SLC2A4LMNASLC2A8PPARA
SCHEMBL6073152 0.94 SLC2A1 (0.49) SLC2A1SLC2A4LMNASLC2A8PPARA
SCHEMBL6073095 0.93 PPARG (0.52) SLC2A1SLC2A4LMNAPPARAPPARG
SCHEMBL6073162 0.92 PPARA (0.43) SLC2A1SLC2A4LMNASLC2A8PPARA
SCHEMBL6073133 0.91 PPARG (0.49) SLC2A1SLC2A4LMNAPPARAPPARG
SCHEMBL6073085 0.91 LMNA (0.44) SLC2A1SLC2A4LMNASLC2A8PPARA
SCHEMBL6073127 0.91 PPARA (0.52) SLC2A1SLC2A4LMNASLC2A8PPARA
SCHEMBL6073078 0.90 PPARG (0.45) SLC2A1SLC2A4LMNASLC2A8PPARA
SCHEMBL6073005 0.89 PPARA (0.49) LMNAPPARAPPARGTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006117743-A1 SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO claimed
WO-2006117743-A1 SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO disclosed