Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.50 |
| ▸ | PPARA | Q07869 | 17/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 11/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.46 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6072990 | 0.95 | SLC2A1 (0.48) | PPARGPPARASLC2A1CYP2C9KCNH2 | |
| SCHEMBL6073074 | 0.95 | PPARA (0.46) | PPARGPPARASLC2A1CYP2C9KCNH2 | |
| SCHEMBL6073152 | 0.94 | SLC2A1 (0.49) | PPARGPPARASLC2A1CYP2C9KCNH2 | |
| SCHEMBL6073095 | 0.93 | PPARG (0.52) | PPARGPPARASLC2A1CYP2C9KCNH2 | |
| SCHEMBL6073162 | 0.93 | PPARA (0.43) | PPARGPPARASLC2A1CYP2C9KCNH2 | |
| SCHEMBL6073105 | 0.91 | PPARG (0.59) | PPARGPPARASLC2A1CYP2C9KCNH2 | |
| SCHEMBL6073008 | 0.91 | PPARG (0.47) | PPARGPPARASLC2A1 | |
| SCHEMBL6073078 | 0.90 | PPARG (0.45) | PPARGPPARASLC2A1CYP2C9KCNH2 | |
| SCHEMBL6073240 | 0.89 | TDP1 (0.43) | PPARGPPARASLC2A1SLC2A4LMNA | |
| SCHEMBL6073005 | 0.89 | PPARA (0.49) | PPARGPPARALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | claimed |
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |