⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265845 | 1.00 | — | — | |
| SCHEMBL6264783 | 1.00 | — | — | |
| SCHEMBL7454104 | 1.00 | — | — | |
| SCHEMBL6267915 | 1.00 | — | — | |
| SCHEMBL13103799 | 0.89 | SLC6A12 (0.46) | — | |
| SCHEMBL7813782 | 0.87 | SLC6A12 (0.65) | — | |
| SCHEMBL11521796 | 0.87 | SLC6A12 (0.65) | — | |
| SCHEMBL28961634 | 0.87 | SLC6A12 (0.65) | — | |
| SCHEMBL31742462 | 0.81 | ALOX5 (0.50) | — | |
| SCHEMBL29099881 | 0.80 | SLC6A12 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871179-B2 | Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid | THE GENERAL HOSPITAL CORPORATION (US) | 2014-10-28 | — | — | US | disclosed |
| US-20080214822-A1 | Process For the Preparation of a Leukotriene Antagonist | MEDICHEM, S.A. (ES) | 2008-09-04 | — | — | US | disclosed |
| US-7067488-B2 | Modified GLP-1 peptides with increased biological potency | THERATECHNOLOGIES INC. (CA) | 2006-06-27 | — | — | US | disclosed |
| EP-1109909-B1 | GRF ANALOGS WITH INCREASED BIOLOGICAL POTENCY | THERATECHNOLOGIES INC (CA) | 2005-11-30 | — | — | EP | disclosed |
| US-20040171534-A1 | GRF analogs with increased biological potency | THERATECHNOLOGIES, INC. (CA) | 2004-09-02 | — | — | US | disclosed |
| US-6458764-B1 | CHIMERIC FATTY BODY-GRF ANALOGS WITH INCREASED BIOLOGICAL POTENCY, THEIR APPLICATION AS ANABOLIC AGENTS AND IN THE DIAGNOSIS AND TREATMENT OF GROWTH HORMONE DEFICIENCIES. THE CHIMERIC FATTY BODY-GRF ANALOGS INCLUDE AN HYDROPHOBIC MOIETY | THERATECHNOLOGIES INC. (CA) | 2002-10-01 | — | — | US | disclosed |
| EP-1109909-A2 | GRF ANALOGS WITH INCREASED BIOLOGICAL POTENCY | THERATECHNOLOGIES INC. (CA) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000014236-A2 | GRF ANALOGS WITH INCREASED BIOLOGICAL POTENCY | THERATECHNOLOGIES INC. (CA) | 2000-03-16 | — | — | WO | disclosed |