Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788843 | 1.00 | LMNA (0.45) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL11543708 | 1.00 | LMNA (0.45) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6073037 | 1.00 | LMNA (0.45) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6073034 | 1.00 | LMNA (0.45) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL23835356 | 0.87 | CYP1A2 (0.46) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL23835355 | 0.87 | CYP1A2 (0.46) | LMNAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL11537365 | 0.85 | RAB9A (0.51) | KDM4EALDH1A1MAPTGRIN2DGRIN3B | |
| SCHEMBL2984290 | 0.80 | KMT2A (0.51) | LMNAALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL2984292 | 0.80 | KMT2A (0.51) | LMNAALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL9734293 | 0.80 | KMT2A (0.51) | LMNAALDH1A1MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006069798-A1 | PROCESS FOR THE PREPARATION OF CHIRAL AMINES | DSM IP ASSETS B.V. (NL) | 2006-07-06 | — | — | WO | disclosed |