Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5396633 | 0.83 | KMT2A (0.53) | KDM4EL3MBTL1TSHRKMT2AMEN1 | |
| SCHEMBL3616171 | 0.77 | HDAC1 (0.50) | HDAC1HDAC8HDAC6CYP2C19KMT2A | |
| SCHEMBL5637435 | 0.76 | NPY1R (0.58) | HDAC1HDAC8HDAC6ACE | |
| SCHEMBL4489025 | 0.74 | SRC (0.58) | HDAC1HDAC8HDAC6CYP2C19KMT2A | |
| SCHEMBL22399618 | 0.72 | FUCA1 (0.50) | KDM4EL3MBTL1KMT2APOLB | |
| SCHEMBL20722883 | 0.72 | CCKBR (0.47) | CCKBRTSHRHPGDCYP2C19KMT2A | |
| SCHEMBL14502147 | 0.71 | KMT2A (0.53) | L3MBTL1TSHRHPGDKMT2AMEN1 | |
| SCHEMBL22368471 | 0.70 | KDM4E (0.45) | KDM4EL3MBTL1TSHRHPGDCYP2C19 | |
| SCHEMBL19990745 | 0.70 | KDM4E (0.45) | KDM4EL3MBTL1TSHRHPGDCYP2C19 | |
| SCHEMBL19990744 | 0.70 | KDM4E (0.45) | KDM4EL3MBTL1TSHRHPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006076568-A2 | THIAZOLOPYRIDINES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-20 | — | — | WO | disclosed |