Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074184 | 1.00 | SLC6A4 (0.47) | SLC6A4SLC6A3SLC6A2CYP2D6ATM | |
| SCHEMBL8954369 | 0.81 | HSD17B10 (0.46) | SLC6A4SLC6A3SLC6A2CYP2D6ATM | |
| SCHEMBL7433120 | 0.79 | POLB (0.45) | SLC6A4SLC6A3SLC6A2CYP2D6ATM | |
| SCHEMBL7433127 | 0.79 | POLB (0.45) | SLC6A4SLC6A3SLC6A2CYP2D6ATM | |
| SCHEMBL7433122 | 0.79 | POLB (0.45) | SLC6A4SLC6A3SLC6A2CYP2D6ATM | |
| SCHEMBL8262931 | 0.79 | SLC6A2 (0.49) | SLC6A4SLC6A3SLC6A2CYP2D6CYP3A4 | |
| SCHEMBL27298881 | 0.77 | SLC6A2 (0.50) | SLC6A4SLC6A3SLC6A2CYP2D6CYP3A4 | |
| SCHEMBL7654723 | 0.77 | SLC6A2 (0.50) | SLC6A4SLC6A3SLC6A2CYP2D6CYP3A4 | |
| SCHEMBL9294530 | 0.77 | SLC6A2 (0.50) | SLC6A4SLC6A3SLC6A2CYP2D6CYP3A4 | |
| SCHEMBL2504396 | 0.76 | HDAC4 (0.61) | SLC6A4SLC6A3SLC6A2CYP2D6ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7119207-B2 | Benzoamide piperidine containing compounds and related compounds | PFIZER INC (US) | 2006-10-10 | — | — | US | disclosed |