Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | CCL2 | P13500 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KLK7 | P49862 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074357 | 1.00 | BRD4 (0.36) | BRD4CCL2ALDH1A1HTTMAOA | |
| SCHEMBL6074065 | 1.00 | BRD4 (0.36) | BRD4CCL2ALDH1A1HTTMAOA | |
| SCHEMBL13802584 | 0.81 | BRD4 (0.37) | BRD4CCL2ALDH1A1HTTMAPK1 | |
| SCHEMBL6073770 | 0.77 | ALDH1A1 (0.43) | BRD4CCL2ALDH1A1HTTTSHR | |
| SCHEMBL5165016 | 0.77 | ALDH1A1 (0.43) | BRD4CCL2ALDH1A1HTTTSHR | |
| SCHEMBL6074170 | 0.77 | ALDH1A1 (0.43) | BRD4CCL2ALDH1A1HTTTSHR | |
| SCHEMBL4148886 | 0.77 | ALDH1A1 (0.43) | BRD4CCL2ALDH1A1HTTTSHR | |
| SCHEMBL4942493 | 0.71 | LMNA (0.48) | BRD4ALDH1A1TSHR | |
| SCHEMBL4939523 | 0.69 | — | — | |
| SCHEMBL32675619 | 0.64 | MEN1 (0.54) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030087925-A1 | Benzoamide piperidine containing compounds and related compounds | PFIZER INC. | 2003-05-08 | — | — | US | claimed |
| US-7119207-B2 | Benzoamide piperidine containing compounds and related compounds | PFIZER INC (US) | 2006-10-10 | — | — | US | disclosed |
| US-20030087925-A1 | Benzoamide piperidine containing compounds and related compounds | PFIZER INC. | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087925-A1 | Benzoamide piperidine containing compounds and related compounds | TACR1, VIPR1, VIPR2 | BRD4 828/4885CCL2 521/4885ALDH1A1 732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.