Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074166 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPTKDM4EGAAALOX15 | |
| SCHEMBL26098146 | 0.74 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTGAALMNAHTT | |
| SCHEMBL6074173 | 0.69 | KDM4E (0.39) | SMN1; SMN2MAPTKDM4EGAAALOX15 | |
| SCHEMBL6075177 | 0.67 | HDAC3 (0.39) | SMN1; SMN2MAPTKDM4EGAAALOX15 | |
| SCHEMBL6075183 | 0.67 | HDAC3 (0.39) | SMN1; SMN2MAPTKDM4EGAAALOX15 | |
| SCHEMBL1359510 | 0.65 | ALDH1A1 (0.65) | SMN1; SMN2MAPTGAAALOX15HTT | |
| SCHEMBL7242058 | 0.65 | CTSL (0.47) | SMN1; SMN2MAPTKDM4EGAAMEN1 | |
| SCHEMBL30817405 | 0.65 | MAPT (0.50) | SMN1; SMN2MAPTKDM4EGAATSHR | |
| SCHEMBL3958945 | 0.64 | HPGD (0.50) | GAALMNAHTTMAPK1TSHR | |
| SCHEMBL6799822 | 0.64 | MAPT (0.38) | SMN1; SMN2MAPTGAALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022716-B2 | Cyclic amine phenyl beta-3 adrenergic receptor agonists | WYETH (US) | 2006-04-04 | — | — | US | disclosed |