Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 7/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | IGF1R | P08069 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074126 | 0.84 | ADRB3 (0.44) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL6074122 | 0.84 | ADRB3 (0.44) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL6074120 | 0.84 | ADRB3 (0.44) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL6074480 | 0.84 | ADRB3 (0.54) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL6074253 | 0.82 | ADRB3 (0.63) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL6074472 | 0.82 | ADRB3 (0.52) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL27598448 | 0.80 | ADRB3 (0.43) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL27598449 | 0.80 | ADRB3 (0.43) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL6074081 | 0.80 | ADRB3 (0.75) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6074589 | 0.80 | ADRB3 (0.45) | ADRB3ADRB1ADRB2ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022716-B2 | Cyclic amine phenyl beta-3 adrenergic receptor agonists | WYETH (US) | 2006-04-04 | — | — | US | disclosed |
| US-6525202-B2 | E.g., substituted (4-amino-5-hydroxyphenyl)-oxy-)piperidinyl thiazolidin-2,4-dione; antidiabetic agents; atherosclerosis, gastrointestinal, metabolic disorders, glaucoma, neurogenetic inflammation, ocular hypertension and frequent urination | WYETH | 2003-02-25 | — | — | US | disclosed |
| US-20020028835-A1 | Cyclic amine phenyl beta-3 adrenergic receptor agonists | WYETH | 2002-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028835-A1 | Cyclic amine phenyl beta-3 adrenergic receptor agonists | ADRB1, ADRB3, ADRB2 | ADRB3 2/4885ADRB1 1/4885ADRB2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.