Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 12/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074786 | 1.00 | TACR1 (0.47) | TACR1TRIM24TRPV1CYP2D6CYP3A4 | |
| SCHEMBL6074289 | 0.92 | TACR1 (0.47) | TACR1TRIM24TRPV1CYP2D6 | |
| SCHEMBL6074431 | 0.90 | TACR1 (0.46) | TACR1TRIM24TRPV1CYP2D6 | |
| SCHEMBL6074434 | 0.90 | TACR1 (0.46) | TACR1TRIM24TRPV1CYP2D6 | |
| SCHEMBL6074619 | 0.89 | TACR1 (0.45) | TACR1TRIM24TRPV1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6073538 | 0.88 | TACR1 (0.44) | TACR1TRIM24TRPV1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6073543 | 0.88 | TACR1 (0.44) | TACR1TRIM24TRPV1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7114291 | 0.88 | TACR1 (0.44) | TACR1TRIM24TRPV1CYP2D6 | |
| SCHEMBL6073577 | 0.87 | TACR1 (0.51) | TACR1TRIM24TRPV1CYP2D6 | |
| SCHEMBL6073746 | 0.87 | TACR1 (0.45) | TACR1TRIM24TRPV1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7119207-B2 | Benzoamide piperidine containing compounds and related compounds | PFIZER INC (US) | 2006-10-10 | — | — | US | disclosed |
| US-20030087925-A1 | Benzoamide piperidine containing compounds and related compounds | PFIZER INC. | 2003-05-08 | — | — | US | disclosed |
| EP-1272484-A2 | BENZOAMIDE PIPERIDINE COMPOUNDS AS SUBSTANCE P ANTAGONISTS | Pfizer Products Inc. (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001077100-A2 | BENZOAMIDE PIPERIDINE COMPOUNDS AS SUBSTANCE P ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2001-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087925-A1 | Benzoamide piperidine containing compounds and related compounds | TACR1, VIPR1, VIPR2 | TACR1 1/4885TRIM24 4522/4885TRPV1 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.