Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 12/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074300 | 1.00 | TACR1 (0.47) | TACR1TRIM24TRPV1CYP2D6CYP3A4 | |
| SCHEMBL6074289 | 0.92 | TACR1 (0.47) | TACR1TRIM24TRPV1CYP2D6 | |
| SCHEMBL6074431 | 0.90 | TACR1 (0.46) | TACR1TRIM24TRPV1CYP2D6 | |
| SCHEMBL6074434 | 0.90 | TACR1 (0.46) | TACR1TRIM24TRPV1CYP2D6 | |
| SCHEMBL6074619 | 0.89 | TACR1 (0.45) | TACR1TRIM24TRPV1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6073538 | 0.88 | TACR1 (0.44) | TACR1TRIM24TRPV1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6073543 | 0.88 | TACR1 (0.44) | TACR1TRIM24TRPV1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7114291 | 0.88 | TACR1 (0.44) | TACR1TRIM24TRPV1CYP2D6 | |
| SCHEMBL6073577 | 0.87 | TACR1 (0.51) | TACR1TRIM24TRPV1CYP2D6 | |
| SCHEMBL6073746 | 0.87 | TACR1 (0.45) | TACR1TRIM24TRPV1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7119207-B2 | Benzoamide piperidine containing compounds and related compounds | PFIZER INC (US) | 2006-10-10 | — | — | US | disclosed |