Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 17/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074434 | 1.00 | TACR1 (0.46) | TACR1CYP2D6TRIM24KCNH2MTNR1B | |
| SCHEMBL6074289 | 0.90 | TACR1 (0.47) | TACR1CYP2D6TRIM24TRPV1 | |
| SCHEMBL6074786 | 0.90 | TACR1 (0.47) | TACR1CYP2D6TRIM24TRPV1 | |
| SCHEMBL6074300 | 0.90 | TACR1 (0.47) | TACR1CYP2D6TRIM24TRPV1 | |
| SCHEMBL6074619 | 0.87 | TACR1 (0.45) | TACR1CYP2D6TRIM24TRPV1 | |
| Hydrochloric Acid SCHEMBL7114291 | 0.86 | TACR1 (0.44) | TACR1CYP2D6TRIM24TRPV1 | |
| Hydrochloric Acid SCHEMBL6073538 | 0.86 | TACR1 (0.44) | TACR1CYP2D6TRIM24TRPV1 | |
| Hydrochloric Acid SCHEMBL6073543 | 0.86 | TACR1 (0.44) | TACR1CYP2D6TRIM24TRPV1 | |
| SCHEMBL6606866 | 0.85 | TACR1 (0.45) | TACR1CYP2D6TRIM24TRPV1 | |
| SCHEMBL8664244 | 0.85 | TACR1 (0.45) | TACR1CYP2D6TRIM24TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7119207-B2 | Benzoamide piperidine containing compounds and related compounds | PFIZER INC (US) | 2006-10-10 | — | — | US | disclosed |