Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 18/20 | 0.50 |
| ▸ | FEN1 | P39748 | 17/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6075271 | 0.84 | ALOX5AP (0.53) | ALOX5APFEN1 | |
| SCHEMBL15256072 | 0.83 | NPC1 (0.55) | — | |
| SCHEMBL5550517 | 0.81 | ALOX5AP (0.53) | ALOX5APFEN1 | |
| SCHEMBL11376072 | 0.80 | FEN1 (0.51) | ALOX5APFEN1 | |
| SCHEMBL6074829 | 0.80 | ALOX5AP (0.49) | ALOX5APFEN1 | |
| SCHEMBL23667869 | 0.78 | CCR1 (0.48) | TLR8 | |
| SCHEMBL15915844 | 0.78 | FEN1 (0.58) | ALOX5APFEN1 | |
| SCHEMBL4477259 | 0.78 | ALOX5AP (0.49) | ALOX5APFEN1 | |
| SCHEMBL15750875 | 0.76 | NNMT (0.47) | ALOX5APFEN1 | |
| SCHEMBL6074984 | 0.76 | ALOX5AP (0.48) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6995161-B2 | Substituted arylpyrazines | NEUROGEN CORPORATION (US) | 2006-02-07 | — | — | US | disclosed |