Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 18/20 | 0.49 |
| ▸ | FEN1 | P39748 | 17/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6075271 | 0.80 | ALOX5AP (0.53) | ALOX5APFEN1MAPT | |
| SCHEMBL6074920 | 0.80 | ALOX5AP (0.50) | ALOX5APFEN1 | |
| SCHEMBL5550517 | 0.77 | ALOX5AP (0.53) | ALOX5APFEN1MAPT | |
| SCHEMBL28371574 | 0.74 | NPC1 (0.46) | MAPT | |
| SCHEMBL16879692 | 0.71 | DYRK1A (0.49) | MAPT | |
| SCHEMBL168656 | 0.71 | NPC1 (0.53) | ALOX5APFEN1MAPT | |
| SCHEMBL404674 | 0.70 | ALDH1A1 (0.52) | MAPT | |
| SCHEMBL15707627 | 0.70 | DRD1 (0.56) | MAPT | |
| SCHEMBL2643818 | 0.69 | KDM1A (0.53) | ALOX5APFEN1 | |
| SCHEMBL28802576 | 0.68 | MAOA (0.49) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6995161-B2 | Substituted arylpyrazines | NEUROGEN CORPORATION (US) | 2006-02-07 | — | — | US | disclosed |