Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30424337 | 0.73 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL77405 | 0.73 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL29475172 | 0.67 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL56979 | 0.67 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL2338077 | 0.67 | MEN1 (0.58) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL11760932 | 0.64 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL1415118 | 0.64 | HKDC1 (0.50) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL11661116 | 0.62 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL9182503 | 0.61 | CYP19A1 (0.56) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL1951372 | 0.60 | MAPT (0.56) | ALDH1A1MEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015334-B2 | A reactant/solvent dimethyl formamide is made slightly basic, heating the solution to reduce the water content, then cooling, adding the hexanitrostilbene, heating to a predetermined temperature, cooling and filtering to accumulate 2,4,7,9-tetranitro-10H-benzo[4,5]furo[3,2]indole product | BWXT PANTEX, LLC (US) | 2006-03-21 | — | — | US | claimed |
| US-20060025603-A1 | A reactant/solvent dimethyl formamide is made slightly basic, heating the solution to reduce the water content, then cooling, adding the hexanitrostilbene, heating to a predetermined temperature, cooling and filtering to accumulate 2,4,7,9-tetranitro-10H-benzo[4,5]furo[3,2]indole product | U.S. DEPARTMENT OF ENERGY | 2006-02-02 | — | — | US | claimed |