⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL21635219 | 0.75 | — | — | |
| Phosphoric Acid SCHEMBL11050140 | 0.75 | — | — | |
| Phosphoric Acid SCHEMBL5907 | 0.72 | CA2 (0.56) | — | |
| Phosphoric Acid SCHEMBL8851940 | 0.72 | CA2 (0.56) | — | |
| Phosphoric Acid SCHEMBL8844890 | 0.72 | CA2 (0.56) | — | |
| Phosphoric Acid SCHEMBL1332284 | 0.72 | — | — | |
| Phosphoric Acid SCHEMBL3788505 | 0.72 | CA2 (0.56) | — | |
| Phosphoric Acid SCHEMBL22 | 0.72 | — | — | |
| Phosphoric Acid SCHEMBL897840 | 0.72 | CA2 (0.56) | — | |
| Phosphoric Acid SCHEMBL36090 | 0.72 | CA2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012078416-A2 | MONOPHOSPHATE PRODRUGS OF DAPD AND ANALOGS THEREOF | RFS PHARMA, LLC (US) | 2012-06-14 | — | — | WO | claimed |
| US-20120142627-A1 | MONOPHOSPHATE PRODRUGS OF DAPD AND ANALOGS THEREOF | EMORY UNIVERSITY (US) | 2012-06-07 | — | — | US | claimed |
| US-9173893-B2 | Purine nucleoside monophosphate prodrugs for treatment of cancer and viral infections | COCRYSTAL PHARMA, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-20140066395-A1 | PURINE NUCLEOSIDE MONOPHOSPHATE PRODRUGS FOR TREATMENT OF CANCER AND VIRAL INFECTIONS | EMORY UNIVERSITY (US) | 2014-03-06 | — | — | US | disclosed |
| US-8609627-B2 | Purine nucleoside monophosphate prodrugs for treatment of cancer and viral infections | RFS PHARMA, LLC (US) | 2013-12-17 | — | — | US | disclosed |
| WO-2012078416-A2 | MONOPHOSPHATE PRODRUGS OF DAPD AND ANALOGS THEREOF | RFS PHARMA, LLC (US) | 2012-06-14 | — | — | WO | disclosed |
| US-20120142627-A1 | MONOPHOSPHATE PRODRUGS OF DAPD AND ANALOGS THEREOF | EMORY UNIVERSITY (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120040924-A1 | PURINE NUCLEOSIDE MONOPHOSPHATE PRODRUGS FOR TREATMENT OF CANCER AND VIRAL INFECTIONS | EMORY UNIVERSITY (US) | 2012-02-16 | — | — | US | disclosed |
| EP-2393815-A2 | PURINE NUCLEOSIDE MONOPHOSPHATE PRODRUGS FOR TREATMENT OF CANCER AND VIRAL INFECTIONS | RFS Pharma, LLC. (US) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010091386-A2 | PURINE NUCLEOSIDE MONOPHOSPHATE PRODRUGS FOR TREATMENT OF CANCER AND VIRAL INFECTIONS | RFS PHARMA, LLC (US) | 2010-08-12 | — | — | WO | disclosed |