Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PGK1 | P00558 | 2/20 | 0.33 |
| ▸ | PGK2 | P07205 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL9126 | 1.00 | CA2 (0.56) | CA2SLC34A1FDPSBLMTDP1 | |
| Phosphoric Acid SCHEMBL8851940 | 1.00 | CA2 (0.56) | CA2SLC34A1FDPSBLMTDP1 | |
| Phosphoric Acid SCHEMBL140393 | 1.00 | CA2 (0.56) | CA2SLC34A1FDPSBLMTDP1 | |
| Phosphoric Acid SCHEMBL1332284 | 1.00 | — | — | |
| Phosphoric Acid SCHEMBL22 | 1.00 | — | — | |
| Phosphoric Acid SCHEMBL8844890 | 1.00 | CA2 (0.56) | CA2SLC34A1FDPSBLMTDP1 | |
| Phosphoric Acid SCHEMBL3788505 | 1.00 | CA2 (0.56) | CA2SLC34A1FDPSBLMTDP1 | |
| Phosphoric Acid SCHEMBL5907 | 1.00 | CA2 (0.56) | CA2SLC34A1FDPSBLMTDP1 | |
| Phosphoric Acid SCHEMBL36090 | 1.00 | CA2 (0.56) | CA2SLC34A1FDPSBLMTDP1 | |
| Phosphoric Acid SCHEMBL45358 | 1.00 | CA2 (0.56) | CA2SLC34A1FDPSBLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240209432-A1 | POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION | Roche Sequencing Solutions, Inc. (US) | 2024-06-27 | — | — | US | disclosed |
| CN-112204154-B | Enzymatic enrichment of DNA-pore-polymerase complexes | 豪夫迈·罗氏有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-115052882-B | Composition for reducing template penetration into nanopores | 豪夫迈·罗氏有限公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-4303314-A2 | POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION | F. Hoffmann-La Roche AG (CH) | 2024-01-10 | — | — | EP | disclosed |
| US-11739378-B2 | Polypeptide tagged nucleotides and use thereof in nucleic acid sequencing by nanopore detection | Roche Sequencing Solutions, Inc. (US) | 2023-08-29 | — | — | US | disclosed |
| CN-109863161-B | Labeled polynucleotides useful for nucleic acid sequencing | 豪夫迈·罗氏有限公司 | 2022-06-03 | — | — | CN | disclosed |
| US-20220090189-A1 | POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION | Roche Sequencing Solutions, Inc. (US) | 2022-03-24 | — | — | US | disclosed |
| CN-108350017-B | Polypeptide-labeled nucleotides and their use in nucleic acid sequencing by nanopore detection | 豪夫迈·罗氏有限公司 | 2022-03-15 | — | — | CN | disclosed |
| US-20210317521-A1 | TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION | Roche Sequencing Solutions, Inc. (US) | 2021-10-14 | — | — | US | disclosed |
| US-20210292832-A1 | TAGGED MULTI-NUCLEOTIDES USEFUL FOR NUCLEIC ACID SEQUENCING | Roche Sequencing Solutions, Inc. (US) | 2021-09-23 | — | — | US | disclosed |
| EP-3347366-A1 | POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION | H. Hoffnabb-La Roche Ag (CH) | 2018-07-18 | — | — | EP | disclosed |
| WO-2018037096-A1 | TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2018-03-01 | — | — | WO | disclosed |
| US-20180057870-A1 | TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION | Roche Sequencing Solutions, Inc. | 2018-03-01 | — | — | US | disclosed |
| WO-2017202917-A1 | TAGGED MULTI-NUCLEOTIDES USEFUL FOR NUCLEIC ACID SEQUENCING | F. HOFFMANN-LA ROCHE AG (CH) | 2017-11-30 | — | — | WO | disclosed |
| US-20170342485-A1 | TAGGED MULTI-NUCLEOTIDES USEFUL FOR NUCLEIC ACID SEQUENCING | Roche Sequencing Solutions, Inc. (US) | 2017-11-30 | — | — | US | disclosed |
| WO-2017203059-A1 | TAGGED MULTI-NUCLEOTIDES USEFUL FOR NUCLEIC ACID SEQUENCING | F. HOFFMANN-LA ROCHE AG (CH) | 2017-11-30 | — | — | WO | disclosed |
| WO-2017042038-A1 | POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2017-03-16 | — | — | WO | disclosed |
| EP-2621273-A2 | POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES | Normoxys, Inc. (US) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012045009-A2 | POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES | NORMOXYS, INC. (US) | 2012-04-05 | — | — | WO | disclosed |
| US-20070264667-A1 | Method and system for assaying transferase activity | GELLIBOLIAN ROBERT | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739378-B2 | Polypeptide tagged nucleotides and use thereof in nucleic acid sequencing by nanopore detection | NPPA, ANPEP, TENT4A | CA2 4445/4885SLC34A1 189/4885FDPS 2103/4885 |
| US-20220090189-A1 | POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION | NPPA, ANPEP, TENT4A | CA2 4445/4885SLC34A1 189/4885FDPS 2103/4885 |
| US-20180057870-A1 | TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION | PHAX, POLRMT, POLN | CA2 3094/4885SLC34A1 33/4885FDPS 1753/4885 |
| US-20210292832-A1 | TAGGED MULTI-NUCLEOTIDES USEFUL FOR NUCLEIC ACID SEQUENCING | NT5C3B, POLN, RNGTT | CA2 4082/4885SLC34A1 271/4885FDPS 376/4885 |
| US-20210317521-A1 | TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION | PHAX, POLRMT, POLN | CA2 3094/4885SLC34A1 33/4885FDPS 1753/4885 |
| US-20240209432-A1 | POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION | NPPA, ANPEP, TENT4A | CA2 4445/4885SLC34A1 189/4885FDPS 2103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.