Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6079968 | 0.92 | PDK2 (0.49) | PDK2HSD11B1CYP2D6CYP2C19KMT2A | |
| SCHEMBL6079254 | 0.91 | PDK2 (0.49) | PDK2HSD11B1CYP2D6KMT2AALDH1A1 | |
| SCHEMBL6079673 | 0.91 | PDK2 (0.49) | PDK2HSD11B1CYP2D6NPY5R | |
| SCHEMBL6080112 | 0.90 | HSD11B1 (0.46) | PDK2HSD11B1CYP2D6CYP2C19MAPK1 | |
| SCHEMBL6080101 | 0.89 | PDK2 (0.43) | PDK2HSD11B1CYP2D6NPY5RMAPT | |
| SCHEMBL6079386 | 0.88 | PDK2 (0.47) | PDK2HSD11B1CYP2D6NPY5R | |
| SCHEMBL6080216 | 0.88 | HSD11B1 (0.41) | PDK2HSD11B1CYP2D6NPY5R | |
| SCHEMBL6080379 | 0.88 | ALDH1A1 (0.46) | PDK2HSD11B1CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL6080840 | 0.88 | PDK2 (0.46) | PDK2HSD11B1CYP2D6NPY5RMAPT | |
| SCHEMBL6080480 | 0.87 | HSD11B1 (0.44) | HSD11B1CYP2D6NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060009471-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2006-01-12 | — | — | US | claimed |
| US-20060009471-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009471-A1 | Amido compounds and their use as pharmaceuticals | HSD11B1, CYP11B1, HSD11B2 | PDK2 988/4885HSD11B1 1/4885CYP2D6 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.