Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2199410 | 0.75 | KDM4E (0.51) | MAPK14SYKEGFRBRAFKDR | |
| SCHEMBL5755028 | 0.69 | KDM4E (0.71) | KDM4EALDH1A1TP53TSHREPHX2 | |
| SCHEMBL1958577 | 0.68 | KDM4E (0.56) | KDM4EALDH1A1TP53TSHREPHX2 | |
| SCHEMBL7314464 | 0.67 | KDM4E (0.64) | KDM4EALDH1A1TP53TSHREPHX2 | |
| SCHEMBL14578174 | 0.66 | EPHX2 (0.61) | SYKKDM4EALDH1A1TP53TSHR | |
| SCHEMBL29417693 | 0.65 | KDM4E (0.62) | KDM4EALDH1A1TP53TSHR | |
| SCHEMBL210600 | 0.65 | KDM4E (0.62) | KDM4EALDH1A1TP53TSHR | |
| SCHEMBL2100906 | 0.65 | ALDH1A1 (0.48) | KDM4EALDH1A1 | |
| SCHEMBL1419893 | 0.65 | CA12 (0.57) | KDM4EALDH1A1TP53TSHR | |
| SCHEMBL5141412 | 0.63 | TSHR (0.67) | KDM4EALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060166990-A1 | Novel aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166990-A1 | Novel aminobenzophenone compounds | NFKBIA, UACA, ALDH7A1 | MAPK14 697/4885SYK 3205/4885EGFR 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.