Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KLK3 | P07288 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6079951 | 0.84 | PARP1 (0.35) | TDP1KDM4E | |
| SCHEMBL6601268 | 0.78 | GPR35 (0.36) | TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL6080679 | 0.75 | TSHR (0.49) | TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL6080643 | 0.75 | KMT2A (0.38) | TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL6080033 | 0.73 | PTPN11 (0.39) | TSHRALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL6080463 | 0.72 | TSHR (0.46) | TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL6080152 | 0.72 | FBP1 (0.49) | TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL6593355 | 0.69 | GPR35 (0.39) | TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL6593362 | 0.69 | GPR35 (0.39) | TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL6080761 | 0.68 | MAPT (0.47) | TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | claimed |
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | TSHR 4728/4885ALDH1A1 2726/4885SMN1; SMN2 2666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.