Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | RXRG | P48443 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | IDH2 | P48735 | 1/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588856 | 0.90 | HTT (0.51) | HTTCYP1A2CYP2C9CYP2C19LRRK2 | |
| SCHEMBL6588851 | 0.90 | HTT (0.51) | HTTCYP1A2CYP2C9CYP2C19LRRK2 | |
| SCHEMBL6080348 | 0.85 | LMNA (0.52) | HTTLRRK2ALDH1A1BRD4 | |
| SCHEMBL6080665 | 0.84 | BRD4 (0.46) | HTTKDM4EHPGDKMT2ABRD4 | |
| SCHEMBL6081152 | 0.83 | BRD4 (0.63) | HTTCYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL6079965 | 0.78 | CYP1A2 (0.54) | HTTCYP1A2CYP2C9CYP2C19LRRK2 | |
| SCHEMBL6584410 | 0.76 | LMNA (0.48) | HTTLRRK2KDM4EHPGDALDH1A1 | |
| SCHEMBL6584406 | 0.76 | LMNA (0.48) | HTTLRRK2KDM4EHPGDALDH1A1 | |
| SCHEMBL6588711 | 0.73 | BRD4 (0.46) | HTTKDM4EHPGDKMT2AALDH1A1 | |
| SCHEMBL6588706 | 0.73 | BRD4 (0.46) | HTTKDM4EHPGDKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | HTT 617/4885CYP1A2 117/4885CYP2C9 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.