Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | RXRG | P48443 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591655 | 0.89 | MRGPRX4 (0.47) | MRGPRX4RXRARXRBRXRGPTPN2 | |
| SCHEMBL6080412 | 0.85 | LMNA (0.47) | MRGPRX4LMNAHPGDNOTUMPTGER1 | |
| SCHEMBL6079781 | 0.84 | LMNA (0.46) | MRGPRX4LMNAHPGDNOTUMFFAR4 | |
| SCHEMBL6080335 | 0.84 | LMNA (0.46) | LMNAHPGDRXRARXRBRXRG | |
| SCHEMBL6079823 | 0.79 | LMNA (0.50) | MRGPRX4LMNAHPGDNOTUMHDAC1 | |
| SCHEMBL6080263 | 0.78 | RXRA (0.45) | MRGPRX4RXRARXRBRXRGPTGER1 | |
| SCHEMBL544470 | 0.78 | MRGPRX4 (0.46) | MRGPRX4LMNAHPGDRXRARXRB | |
| SCHEMBL16653066 | 0.75 | MRGPRX4 (0.46) | MRGPRX4LMNAHPGDRXRARXRB | |
| SCHEMBL6079519 | 0.75 | LMNA (0.54) | LMNAHPGDNOTUM | |
| SCHEMBL6080510 | 0.74 | LMNA (0.47) | LMNAHPGDNOTUMPTGER1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | MRGPRX4 238/4885LMNA 2027/4885HPGD 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.