Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4989111 | 0.96 | KMT2A (0.50) | KMT2AALDH1A1MEN1L3MBTL1RAB9A | |
| SCHEMBL3939476 | 0.87 | TSHR (0.46) | KMT2AALDH1A1RAB9AMAPTTSHR | |
| SCHEMBL11284225 | 0.87 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1L3MBTL1RAB9A | |
| SCHEMBL12717220 | 0.87 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1L3MBTL1RAB9A | |
| SCHEMBL10648648 | 0.84 | KMT2A (0.48) | KMT2AALDH1A1MEN1L3MBTL1RAB9A | |
| SCHEMBL3936078 | 0.82 | TSHR (0.51) | KMT2AALDH1A1RAB9AMAPTTSHR | |
| SCHEMBL6528311 | 0.79 | TSHR (0.50) | KMT2AALDH1A1MEN1RAB9ATSHR | |
| SCHEMBL948885 | 0.79 | KMT2A (0.49) | KMT2AALDH1A1MEN1L3MBTL1RAB9A | |
| SCHEMBL21389278 | 0.79 | KMT2A (0.39) | KMT2AALDH1A1MEN1L3MBTL1RAB9A | |
| SCHEMBL27339301 | 0.78 | ALDH1A1 (0.49) | KMT2AALDH1A1MEN1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060089398-A1 | Isoxazole carboxamide derivatives as ghrelin receptor modulators | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089398-A1 | Isoxazole carboxamide derivatives as ghrelin receptor modulators | GPR119, GIPR, GLP1R | KMT2A 1793/4885ALDH1A1 3320/4885MEN1 3388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.