Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 3/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081016 | 0.90 | PDE10A (0.56) | TNKSTNKS2PARP2PDE10ACDK9 | |
| SCHEMBL6081023 | 0.82 | KDM4E (0.52) | TNKSTNKS2PARP2PDE10ACDK9 | |
| SCHEMBL6080957 | 0.81 | PDE10A (0.52) | TNKSTNKS2PARP2PDE10ACDK9 | |
| SCHEMBL6080920 | 0.78 | PDE10A (0.50) | TNKSTNKS2PARP2PDE10ACDK9 | |
| SCHEMBL6080250 | 0.75 | DHODH (0.41) | DHODHKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL6593342 | 0.75 | TNKS (0.52) | TNKSTNKS2PARP2PDE10ADHODH | |
| SCHEMBL6079932 | 0.74 | PDE4B (0.43) | TNKSTNKS2PARP2PDE10ADHODH | |
| SCHEMBL6079388 | 0.72 | PARP1 (0.41) | PDE10ADHODHPARP1KDM4EALDH1A1 | |
| SCHEMBL6718909 | 0.71 | FABP4 (0.56) | KDM4EALDH1A1MAPTKMT2APOLB | |
| SCHEMBL6080253 | 0.70 | KDM4E (0.46) | PDE10AKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | claimed |
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | TNKS 1332/4885TNKS2 1619/4885PARP2 1651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.