Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | IGFBP3 | P17936 | 3/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593208 | 0.83 | MRGPRX4 (0.45) | KMT2ARAB9AMAPT | |
| SCHEMBL6079871 | 0.76 | CCR6 (0.35) | KDM4EKMT2ACYP1A2CCR6GLA | |
| SCHEMBL6081112 | 0.74 | KDM4E (0.40) | KDM4EKMT2ACYP1A2CCR6IGFBP3 | |
| SCHEMBL4309921 | 0.73 | KDM4E (0.49) | KDM4EKMT2ACYP1A2CCR6IGFBP3 | |
| Xanthurenate SCHEMBL379760 | 0.70 | KDM4E (0.59) | KDM4EKMT2ACYP1A2CCR6IGFBP3 | |
| Xanthurenate SCHEMBL29394132 | 0.70 | KDM4E (0.59) | KDM4EKMT2ACYP1A2CCR6IGFBP3 | |
| Xanthurenate SCHEMBL29911018 | 0.70 | KDM4E (0.59) | KDM4EKMT2ACYP1A2CCR6IGFBP3 | |
| SCHEMBL6079537 | 0.70 | KDM4E (0.54) | KDM4EKMT2ACYP1A2IGFBP3FDPS | |
| SCHEMBL6079734 | 0.68 | MMP2 (0.54) | KDM4EKMT2ACYP1A2CCR6IGFBP3 | |
| SCHEMBL6079288 | 0.67 | KDM4E (0.51) | KDM4EKMT2ACYP1A2CCR6IGFBP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | KDM4E 1006/4885KMT2A 1384/4885CYP1A2 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.