Xanthurenate

Xanthurenate

SCHEMBL379760

O=C(O)c1cc(O)c2cccc(O)c2n1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.59
KMT2A Q03164 1/20 0.59
RAB9A P51151 2/20 0.47
KDM4A O75164 2/20 0.47
EGLN1 Q9GZT9 1/20 0.47
HIF1AN Q9NWT6 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALOX15 P16050 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
TSHR P16473 1/20 0.45
ACMSD Q8TDX5 1/20 0.45
CYP1A2 P05177 2/20 0.45
PIM1 P11309 1/20 0.45
IGFBP3 P17936 1/20 0.43
PARP1 P09874 2/20 0.43
TNKS O95271 1/20 0.43
TNKS2 Q9H2K2 1/20 0.43
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthurenate SCHEMBL29911018 1.00 KDM4E (0.59) KDM4EKMT2ARAB9AKDM4AEGLN1
Xanthurenate SCHEMBL29394132 1.00 KDM4E (0.59) KDM4EKMT2ARAB9AKDM4AEGLN1
SCHEMBL6080750 0.85 KDM4E (0.46) KDM4EKMT2ARAB9AKDM4AEGLN1
SCHEMBL6080058 0.85 KDM4E (0.46) KDM4EKMT2ARAB9AALOX15TDP1
SCHEMBL6079537 0.85 KDM4E (0.54) KDM4EKMT2ARAB9AKDM4AEGLN1
SCHEMBL2909426 0.85 KDM4E (0.49) KDM4EKMT2ARAB9AALOX15TDP1
SCHEMBL3333164 0.85 GRM2 (0.48) KDM4EKMT2ARAB9AALOX15TDP1
SCHEMBL6080102 0.85 KDM4E (0.56) KDM4EKMT2ARAB9AKDM4AEGLN1
SCHEMBL6594758 0.85 KDM4E (0.46) KDM4EKMT2ARAB9AKDM4AEGLN1
SCHEMBL5211310 0.84 PIM1 (0.60) KDM4EKMT2ARAB9AKDM4AEGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1533 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260053887-A1 Methods and Kits to Prevent And/Or Treat Cardiac Disorders UNIV IOWA RES FOUND (US) 2026-02-26 US claimed
US-20250367269-A1 KYNURENINE AMINOTRANSFERASE AND PRODUCTS THEREOF FOR THE TREATMENT OF ARTHRITIC DISEASES INSTITUT NATIONAL DE RECH POUR LAGRICULTURE LALIMENTATION ET L’ENVIRONNEMENT (FR) 2025-12-04 US claimed
EP-4648788-A1 LIPID BINDING PROTEIN MOLECULE THERAPY Abionyx Pharma SA (FR) 2025-11-19 EP claimed
EP-4622648-A1 SELECTION OF PATIENTS FOR THE TREATMENT OF FADS1-MEDIATED DISEASES OR DISORDERS USING FADS-1 INHIBITORS Amgen Inc. (US) 2025-10-01 EP claimed
US-20250275954-A1 USE OF KYNURENIC ACID RESISTING HYPERURICEMIA AND STRUCTURAL ANALOG THEREOF IN PREPARATION OF XOD INHIBITOR UNIV JIMEI (CN) 2025-09-04 US claimed
US-20250255792-A1 Methods of Using a Small Molecule Chemical Compound to Reduce the Appearance of Rhytids and Wrinkles BIRCHBIOMED INC. (CA) 2025-08-14 US claimed
EP-4572737-A1 METHODS OF USING A SMALL MOLECULE CHEMICAL COMPOUND TO REDUCE THE APPEARANCE OF RHYTIDS AND WRINKLES Birchbiomed Inc. (CA) 2025-06-25 EP claimed
CN-120195409-A Composition for diagnosing sepsis and medicament for sepsis preventive treatment 北京大学第三医院(北京大学第三临床医学院) 2025-06-24 CN claimed
WO-2025107568-A1 USE OF KYNURENIC ACID IN RESISTING HYPERURICEMIA AND STRUCTURAL ANALOG THEREOF IN PREPARING XOD INHIBITOR 集美大学 2025-05-30 WO claimed
US-20250172571-A1 Biosignatures for Fatigue Syndromes LABORATORIUM M NUYTINCK (BE) 2025-05-29 US claimed
EP-0653680-A2 Photosensitive composition, photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1995-05-17 EP claimed
WO-1995003815-A1 ANTIBODIES SPECIFIC TO QUINOLINIC ACID GEORGETOWN UNIVERSITY (US) 1995-02-09 WO claimed
WO-1995002699-A1 ANALOGUES OF REPORTER GROUPS AS BACKGROUNG REDUCERS IN HYBRIDIZATION ASSAYS APROGENEX, INC. (US) 1995-01-26 WO claimed
EP-0168277-B2 POLY(ORTHOESTER)POLYMERS CONTAINING PENDANT ACID FUNCTIONALITIES AND LABILE BACKBONE BONDS Merck & Co., Inc. (US) 1992-12-30 EP claimed
EP-0168277-B1 Poly(orthoester)polymers containing pendant acid functionalities and labile backbone bonds MERCK & CO. INC. (US) 1990-08-01 EP claimed
US-4765973-A Polymers containing pendant acid functionalities and labile backbone bonds MERCK & CO., INC. (US) 1988-08-23 US claimed
US-4639366-A Polymers containing pendant acid functionalities and labile backbone bonds MERCK & CO., INC. (US) 1987-01-27 US claimed
US-4620850-A HYDROXYBENZOLFURANONE WELLA AKTIENGESELLSCHAFT (DE) 1986-11-04 US claimed
EP-0168277-A1 Poly(orthoester)polymers containing pendant acid functionalities and labile backbone bonds MERCK & CO. INC. (US) 1986-01-15 EP claimed
EP-0026474-B1 COMPOSITION AND PROCESS FOR OXIDATIVE DYEING OF HAIR Wella Aktiengesellschaft (DE) 1983-06-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250275954-A1 USE OF KYNURENIC ACID RESISTING HYPERURICEMIA AND STRUCTURAL ANALOG THEREOF IN PREPARATION OF XOD INHIBITOR XDH, DAO, KMO KDM4E 1180/4885KMT2A 709/4885RAB9A 3688/4885
US-20250367269-A1 KYNURENINE AMINOTRANSFERASE AND PRODUCTS THEREOF FOR THE TREATMENT OF ARTHRITIC DISEASES AADAT, KYNU, KMO KDM4E 1825/4885KMT2A 767/4885RAB9A 3199/4885
US-20260053887-A1 Methods and Kits to Prevent And/Or Treat Cardiac Disorders KYNU, AADAT, TPH1 KDM4E 2313/4885KMT2A 1843/4885RAB9A 1482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.