Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 13/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637769 | 0.84 | GHSR (1.00) | GHSRPTGS2 | |
| SCHEMBL3635879 | 0.84 | GHSR (0.79) | GHSRPTGS2 | |
| SCHEMBL3636499 | 0.81 | GHSR (1.00) | GHSRPTGS2 | |
| SCHEMBL3636109 | 0.80 | GHSR (0.79) | GHSRPTGS2TP53MAPT | |
| SCHEMBL3632135 | 0.80 | GHSR (0.87) | GHSRPTGS2 | |
| SCHEMBL3638189 | 0.79 | GHSR (0.89) | GHSRPTGS2 | |
| SCHEMBL3634973 | 0.79 | GHSR (0.88) | GHSRTP53MAPT | |
| SCHEMBL3637872 | 0.75 | GHSR (0.80) | GHSRPTGS2 | |
| SCHEMBL3637758 | 0.75 | GHSR (1.00) | GHSR | |
| SCHEMBL5158195 | 0.75 | GHSR (1.00) | GHSRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060089398-A1 | Isoxazole carboxamide derivatives as ghrelin receptor modulators | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089398-A1 | Isoxazole carboxamide derivatives as ghrelin receptor modulators | GPR119, GIPR, GLP1R | GHSR 5/4885PTGS2 2925/4885TP53 3018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.