SCHEMBL608158

SCHEMBL608158

C=C(C)C(=O)OC(C)C(=O)CC(C)=O

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
ALDH1A1 P00352 3/20 0.43
THRB P10828 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7167671 0.82 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL27527491 0.77 ALDH1A1 (0.40) TSHRALDH1A1THRBMGAMGAA
SCHEMBL21715153 0.77 TSHR (0.46) TSHRALDH1A1THRBTDP1
SCHEMBL11382030 0.77 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL12936017 0.77 TSHR (0.46) TSHRALDH1A1THRB
SCHEMBL5249209 0.76 TSHR (0.46) TSHRALDH1A1THRBTDP1
SCHEMBL9323497 0.76 TSHR (0.46) TSHRALDH1A1THRBTDP1
SCHEMBL1755554 0.76 TSHR (0.46) TSHRALDH1A1THRBTDP1
SCHEMBL9465458 0.75 MGAM (0.41) TSHRALDH1A1MGAMGAASI
SCHEMBL1657006 0.75 ALDH1A1 (0.52) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10596790-B1 Multilayered elastomeric articles and methods thereof CHEN FUNG BOR (US) 2020-03-24 US claimed
CN-109485774-A A kind of starch base styrene-acrylic emulsion and preparation method thereof 浙江莱科新材料科技有限公司 2019-03-19 CN claimed
CN-109096440-A Water-based latex, preparation method containing the polymer beads with core-shell structure and the coating formed by the water-based latex 广东华润涂料有限公司 2018-12-28 CN claimed
CN-105693907-B The preparation method of the silica containing Janus particles of grain size and asymmetric degree controllably 上海交通大学 2018-06-29 CN claimed
CN-103524966-B Aqueous polymer dispersons for stabilizing actives 罗门哈斯公司 2017-01-18 CN claimed
CN-104004421-B Carpet having surfactant stabilized emulsion polymer carpet binders for improved processability 国际人造丝公司 2016-08-24 CN claimed
CN-105693907-A Preparation method of Janus particle containing silicon dioxide with controllable particle size and asymmetrical degree 上海交通大学 2016-06-22 CN claimed
CN-104004421-A Carpet having surfactant stabilized emulsion polymer carpet binders for improved processability CELANESE INT CORP 2014-08-27 CN claimed
CN-102429834-B Artificial nail compositions and related methods CREATIVE NAIL DESIGN INC 2014-05-07 CN claimed
CN-101490181-B Coating system for cement composite articles VALSPAR SOURCING INC 2013-08-28 CN claimed
CN-101838370-A Aqueous concoction, aqueous polymer emulsion prepared from same and application thereof ETERNAL CHEMICAL CHINA CO LTD 2010-09-22 CN claimed
CN-101490181-A Coating system for cement composite articles VALSPAR SOURCING INC (US) 2009-07-22 CN claimed
CN-101475770-A Scrub and stain-resistant coating ROHM & HAAS (US) 2009-07-08 CN claimed
CN-101379007-A Coating system for cement composite articles VALSPAR SOURCING INC (US) 2009-03-04 CN claimed
CN-1161436-C Coating compositions containing a highly fluorinated polymeric additive ��Ļ���Ű˾ 2004-08-11 CN claimed
CN-1443229-A Adhesive compositions containing stable amino-containing polymer latex blends EASTMAN CHEM CO (US) 2003-09-17 CN claimed
CN-1302199-A Artificial nail compositions and related methods SPAIN SPECIAL COSMETIC SKIN CA (US) 2001-07-04 CN claimed
CN-1279704-A Coating compositions containing highly fluorinated polymer additives DU PONT (US) 2001-01-10 CN claimed
CN-1167773-A Method of producing isocyanate-modified latex polymer ROHM & HAAS (US) 1997-12-17 CN claimed
CN-1106416-A Silane-modified floor finish vehicles ROHM & HAAS (US) 1995-08-09 CN claimed