Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 12/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 10/20 | 0.49 |
| ▸ | PGR | P06401 | 9/20 | 0.49 |
| ▸ | GABRP | O00591 | 5/20 | 0.39 |
| ▸ | GABRD | O14764 | 5/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.39 |
| ▸ | GABRE | P78334 | 5/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407295 | 0.83 | NR3C1 (0.67) | NR3C1NR3C2PGR | |
| SCHEMBL4405157 | 0.83 | NR3C1 (0.54) | NR3C1NR3C2PGRKDM4ELMNA | |
| SCHEMBL4416480 | 0.80 | NR3C1 (0.52) | NR3C1NR3C2PGRKDM4E | |
| SCHEMBL4407293 | 0.78 | NR3C1 (0.60) | NR3C1NR3C2PGRKDM4EMAPT | |
| SCHEMBL4407411 | 0.77 | NR3C1 (0.55) | NR3C1NR3C2PGRKDM4EALDH1A1 | |
| SCHEMBL4407713 | 0.76 | NR3C1 (0.58) | NR3C1NR3C2PGR | |
| SCHEMBL4069020 | 0.76 | NR3C1 (0.62) | NR3C1NR3C2PGR | |
| SCHEMBL4407416 | 0.75 | NR3C1 (0.53) | NR3C1NR3C2PGRALDH1A1MAPT | |
| SCHEMBL2214063 | 0.75 | CNR2 (0.77) | CNR2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4410815 | 0.73 | NR3C1 (0.50) | NR3C1NR3C2PGRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189646-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-08-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189646-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | NR3C1, NR3C2, MC2R | CNR2 492/4885NR3C1 1/4885NR3C2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.