⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249598 | 0.92 | — | — | |
| SCHEMBL10430257 | 0.90 | GPR84 (0.48) | — | |
| SCHEMBL725789 | 0.82 | — | — | |
| SCHEMBL161332 | 0.74 | — | — | |
| SCHEMBL10440474 | 0.74 | TSHR (0.48) | — | |
| SCHEMBL143274 | 0.72 | — | — | |
| SCHEMBL320998 | 0.72 | — | — | |
| SCHEMBL3637885 | 0.72 | — | — | |
| SCHEMBL28003235 | 0.72 | — | — | |
| SCHEMBL202195 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10723754-B2 | 2′,4′-bridged nucleosides for HCV infection | IDENIX PHARMACEUTICALS LLC (US) | 2020-07-28 | — | — | US | disclosed |
| EP-2909222-A1 | 2',4'-BRIDGED NUCLEOSIDES FOR HCV INFECTION | IDENIX Pharmaceuticals, Inc. (US) | 2015-08-26 | — | — | EP | disclosed |
| WO-2014066239-A1 | 2',4'-BRIDGED NUCLEOSIDES FOR HCV INFECTION | IDENIX PHARMACEUTICALS, INC. (US) | 2014-05-01 | — | — | WO | disclosed |
| US-20140112887-A1 | 2',4'-BRIDGED NUCLEOSIDES FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC | 2014-04-24 | — | — | US | disclosed |
| US-7071359-B1 | Neuropathy improvers containing nitrogenous compounds as the active ingredient | TEIJIN LIMITED (JP) | 2006-07-04 | — | — | US | disclosed |
| EP-1201235-B1 | NEUROPATHY IMPROVERS CONTAINING NITROGENOUS COMPOUNDS AS THE ACTIVE INGREDIENT | TEIJIN LTD (JP) | 2005-10-12 | — | — | EP | disclosed |
| EP-1201235-A1 | NEUROPATHY IMPROVERS CONTAINING NITROGENOUS COMPOUNDS AS THE ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 2002-05-02 | — | — | EP | disclosed |