⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10430257 | 0.97 | GPR84 (0.48) | — | |
| SCHEMBL6083665 | 0.92 | — | — | |
| SCHEMBL725789 | 0.80 | — | — | |
| SCHEMBL3429700 | 0.76 | CES2 (0.43) | — | |
| SCHEMBL797999 | 0.76 | TSHR (0.46) | — | |
| SCHEMBL5791951 | 0.74 | TSHR (0.46) | — | |
| SCHEMBL16030163 | 0.74 | TSHR (0.46) | — | |
| SCHEMBL4228159 | 0.74 | — | — | |
| SCHEMBL3037978 | 0.74 | — | — | |
| SCHEMBL142676 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 717 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4351552-A1 | COMBINATION THERAPIES WITH SETD2 INHIBITORS | Epizyme, Inc. (US) | 2024-04-17 | — | — | EP | claimed |
| US-11685723-B2 | Antibacterial agents: O-alkyl-deuterated pyronins | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-06-27 | — | — | US | claimed |
| US-20230101819-A1 | SMYD Inhibitors | EPIZYME INC (US) | 2023-03-30 | — | — | US | claimed |
| US-20230075198-A1 | SUBSTITUTED INDOLES AND METHODS OF USE THEREOF | Epizyme, Inc. | 2023-03-09 | — | — | US | claimed |
| EP-4107157-A1 | SETD2 INHIBITORS AND RELATED METHODS AND USES, INCLUDING COMBINATION THERAPIES | Epizyme, Inc. (US) | 2022-12-28 | — | — | EP | claimed |
| WO-2022261243-A1 | COMBINATION THERAPIES WITH SETD2 INHIBITORS | Epizyme, Inc. (US) | 2022-12-15 | — | — | WO | claimed |
| US-20210198252-A1 | SMYD INHIBITORS | EPIZYME INC (US) | 2021-07-01 | — | — | US | claimed |
| EP-3837240-A1 | SUBSTITUTED INDOLES AND METHODS OF USE THEREOF | Epizyme, Inc. (US) | 2021-06-23 | — | — | EP | claimed |
| EP-3193604-B1 | SUBSTITUTED N-(PYRROLIDIN-3-YL)ISOXAZOLE-3-CARBOXAMIDE COMPOUNDS | EPIZYME INC (US) | 2021-06-16 | — | — | EP | claimed |
| US-20210002246-A1 | ANTIBACTERIAL AGENTS: O-ALKYL-DEUTERATED PYRONINS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2021-01-07 | — | — | US | claimed |
| CN-1117966-A | Biphenyl derivatives | EISAI CO LTD (JP) | 1996-03-06 | — | — | CN | claimed |
| EP-0356412-B1 | USE OF 2-AMINO-4-MORPHOLINO-6-PROPYL-1,3,5-TRIAZINES IN THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF COGNITIVE AND MENTAL DISORDERS | U C B, S.A. (BE) | 1992-05-13 | — | — | EP | claimed |
| US-4956363-A | 2-amino-4-morpholino-6-propyl-1,3,5-triazine | U C B S.A. (BE) | 1990-09-11 | — | — | US | claimed |
| US-4806682-A | Sulfonium salts of diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1989-02-21 | — | — | US | claimed |
| EP-0055562-B1 | CEPHALOSPORIN DERIVATIVES | ICI PHARMA (FR) | 1986-02-12 | — | — | EP | claimed |
| EP-0055099-B1 | PENICILLIN DERIVATIVES | ICI PHARMA (FR) | 1984-10-24 | — | — | EP | claimed |
| EP-0071370-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | ICI PHARMA (FR) | 1983-02-09 | — | — | EP | claimed |
| EP-0055099-A1 | Penicillin derivatives | ICI PHARMA (FR) | 1982-06-30 | — | — | EP | claimed |
| EP-0046289-A2 | Substituted enantholactam derivatives as antihypertensives, a process for preparing and a pharmaceutical composition containing them, and intermediates | MERCK & CO. INC. (US) | 1982-02-24 | — | — | EP | claimed |
| US-3944428-A | Alkaline curing corrugating adhesive | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1976-03-16 | — | — | US | claimed |