SCHEMBL608412

SCHEMBL608412

Cc1cccc(CCl)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
TRPA1 O75762 1/20 0.42
ATM Q13315 1/20 0.42
MAPT P10636 2/20 0.39
TP53 P04637 1/20 0.39
GAA P10253 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
PON1 P27169 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
NPC1 O15118 1/20 0.37
JAK2 O60674 1/20 0.37
TNF P01375 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
NOD1 Q9Y239 1/20 0.37
TSHR P16473 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29668555 1.00 ESR1 (0.44) ESR1ESR2TRPA1ATMMAPT
Ammonia Solution, Strong SCHEMBL251115 0.98 ESR1 (0.43) ESR1ESR2TRPA1ATMMAPT
SCHEMBL3415053 0.98 ESR1 (0.43) ESR1ESR2TRPA1ATMMAPT
Ammonia Solution, Strong SCHEMBL5872057 0.95 ESR1 (0.42) ESR1ESR2TRPA1ATMMAPT
SCHEMBL6914998 0.87 TSHR (0.38) ESR1ESR2TRPA1ATMMAPT
Allylamine SCHEMBL6693480 0.84 ESR1 (0.39) ESR1ESR2TRPA1ATMMAPT
SCHEMBL5973889 0.84 CYP3A4 (0.43) ESR1ESR2TRPA1ATMMAPT
SCHEMBL11855414 0.81 ESR1 (0.42) ESR1ESR2TRPA1ATMMAPT
SCHEMBL28356514 0.81 CD274 (0.44) MAPTTP53GAAMAPK1HSD17B10
Dodecylamine SCHEMBL10778090 0.80 DNM1 (0.42) TAAR1TSHRALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120004749-A Phosphorus binding agent, preparation thereof and application thereof in medicaments for treating hyperphosphatemia 泰州市中医院 2025-05-16 CN claimed
CN-119708491-A Polydisulfide polymer material containing hydroxy ester group and preparation method thereof 衢州化工新材料创新研究院 2025-03-28 CN claimed
CN-119661754-A Synthesis method of narrow-distribution poly-p-acetoxyl styrene and copolymer thereof 青岛科技大学 2025-03-21 CN claimed
CN-117003705-A Novel 1,2, 3-triazole compound with anti-tumor effect, and preparation method and application thereof 北京中医药大学 2023-11-07 CN claimed
CN-114058173-A Process and composition for producing flexible polyurethane foams 赢创运营有限公司 2022-02-18 CN claimed
US-5080767-A Light an dpolyalkylene-amine are present MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-14 US claimed
EP-0391696-A2 Process for preparing aromatic compounds having chlorinated side chains and method for stabilizing monochloro-side chain aromatic compounds MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-10-10 EP claimed
US-4152352-A PRODUCTION OF ARYLPYRUVIC ACIDS RHONE-POULENC INDUSTRIES (FR) 1979-05-01 US claimed
CN-120004749-A Phosphorus binding agent, preparation thereof and application thereof in medicaments for treating hyperphosphatemia 泰州市中医院 2025-05-16 CN disclosed
CN-119708537-A Novel PEDOT aqueous dispersion, preparation method and application thereof 东莞东阳光科研发有限公司 2025-03-28 CN disclosed
CN-119661754-A Synthesis method of narrow-distribution poly-p-acetoxyl styrene and copolymer thereof 青岛科技大学 2025-03-21 CN disclosed
CN-119462317-A Method for preparing 2, 3-dimethyl-2, 3-phenylbutane through continuous flow reaction 浙江工业大学 2025-02-18 CN disclosed
CN-119161580-A Amide group-containing polydisulfide degradable high polymer material and preparation method thereof 衢州化工新材料创新研究院 2024-12-20 CN disclosed
CN-118955941-A PEDOT dispersion and preparation method and application thereof 东莞东阳光科研发有限公司 2024-11-15 CN disclosed
US-4152352-A PRODUCTION OF ARYLPYRUVIC ACIDS RHONE-POULENC INDUSTRIES (FR) 1979-05-01 US disclosed
US-4146384-A Tetrahydrofuran-ether compounds and herbicidal compositions BAYER AKTIENGESELLSCHAFT (DE) 1979-03-27 US disclosed
EP-0000002-A1 Tetrahydrofurane derivatives, processes for their preparation and their use as herbicides BAYER AG (DE) 1978-12-20 EP disclosed
US-3991040-A Aromatic imidodicarboxylic acid diallyl esters, prepolymers thereof, cured resins thereof, and processes for producing these TEIJIN LIMITED (JA) 1976-11-09 US disclosed
US-3933947-A INSECTICIDE, MITICIDE, NEMATOCIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-01-20 US disclosed
US-3931224-A Aromatic imidodicarboxylic acid diallyl esters, prepolymers thereof, cured resins thereof, and processes for producing these TEIJIN LIMITED (JA) 1976-01-06 US disclosed