Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 known ✓ | Q92731 | 1/20 | 0.42 |
| ▸ | JAK2 known ✓ | O60674 | 1/20 | 0.35 |
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.34 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | PON1 | P27169 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL251115 | 0.98 | ESR1 (0.43) | ESR1ESR2PON1TRPA1ATM | |
| SCHEMBL608412 | 0.95 | ESR1 (0.44) | ESR1ESR2PON1TRPA1ATM | |
| SCHEMBL29668555 | 0.95 | ESR1 (0.44) | ESR1ESR2PON1TRPA1ATM | |
| SCHEMBL3415053 | 0.93 | ESR1 (0.43) | ESR1ESR2PON1TRPA1ATM | |
| SCHEMBL6914998 | 0.83 | TSHR (0.38) | ESR1ESR2PON1TRPA1ATM | |
| Allylamine SCHEMBL6693480 | 0.81 | ESR1 (0.39) | ESR1ESR2PON1TRPA1ATM | |
| SCHEMBL5973889 | 0.81 | CYP3A4 (0.43) | ESR1ESR2PON1TRPA1ATM | |
| Ammonia Solution, Strong SCHEMBL514873 | 0.78 | TAAR1 (0.50) | MAPTTAAR1KMT2ATSHRALDH1A1 | |
| SCHEMBL11855414 | 0.77 | ESR1 (0.42) | ESR1ESR2TRPA1ATMMAPT | |
| SCHEMBL28356514 | 0.77 | CD274 (0.44) | MAPTTP53GAAMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250344696-A1 | ACIDIC BIOFILM REMEDIATION | ECOLAB USA INC (US) | 2025-11-13 | — | — | US | disclosed |
| US-20250287943-A1 | PERFORMIC ACID BIOFILM PREVENTION FOR INDUSTRIAL CO2 SCRUBBERS | ECOLAB USA INC. | 2025-09-18 | — | — | US | disclosed |
| US-12396456-B2 | Acidic biofilm remediation | ECOLAB USA INC. (US) | 2025-08-26 | — | — | US | disclosed |
| US-12290071-B2 | Performic acid biofilm prevention for industrial CO2 scrubbers | ECOLAB USA INC. (US) | 2025-05-06 | — | — | US | disclosed |
| US-20240114904-A1 | PERFORMIC ACID BIOFILM PREVENTION FOR INDUSTRIAL CO2 SCRUBBERS | ECOLAB USA INC. | 2024-04-11 | — | — | US | disclosed |
| US-11882826-B2 | Performic acid biofilm prevention for industrial CO2 scrubbers | ECOLAB USA INC. (US) | 2024-01-30 | — | — | US | disclosed |
| US-11844349-B2 | Anti-microbial agent to control biomass accumulation in SO2 scrubbers | ECOLAB USA INC. (US) | 2023-12-19 | — | — | US | disclosed |
| US-20230345939-A1 | ACIDIC BIOFILM REMEDIATION | ECOLAB USA INC. | 2023-11-02 | — | — | US | disclosed |
| US-11723364-B2 | Acidic biofilm remediation | ECOLAB USA INC. (US) | 2023-08-15 | — | — | US | disclosed |
| EP-3442334-B9 | PERFORMIC ACID BIOFILM PREVENTION FOR INDUSTRIAL CO2 SCRUBBERS | ECOLAB USA INC (US) | 2023-08-02 | — | — | EP | disclosed |
| US-10238108-B2 | Acidic biofilm remediation | ECOLAB USA INC. (US) | 2019-03-26 | — | — | US | disclosed |
| EP-3442334-A1 | PERFORMIC ACID BIOFILM PREVENTION FOR INDUSTRIAL CO2 SCRUBBERS | Ecolab USA Inc. (US) | 2019-02-20 | — | — | EP | disclosed |
| US-20180360036-A1 | ACIDIC BIOFILM REMEDIATION | ECOLAB USA INC. | 2018-12-20 | — | — | US | disclosed |
| US-10085447-B2 | Acidic biofilm remediation | ECOLAB USA INC. (US) | 2018-10-02 | — | — | US | disclosed |
| WO-2018075346-A1 | ANTIMICROBIAL COMPOSITION FOR CONTROLLING BIOMASS ACCUMULATION IN SO2 SCRUBBERS | ECOLAB USA INC. (US) | 2018-04-26 | — | — | WO | disclosed |
| US-20180110224-A1 | ANTI-MICROBIAL AGENT TO CONTROL BIOMASS ACCUMULATION IN SO2 SCRUBBERS | ECOLAB USA INC. | 2018-04-26 | — | — | US | disclosed |
| WO-2017181005-A1 | PERFORMIC ACID BIOFILM PREVENTION FOR INDUSTRIAL CO2 SCRUBBERS | ECOLAB USA INC. (US) | 2017-10-19 | — | — | WO | disclosed |
| US-20120232153-A1 | ACIDIC BIOFILM REMEDIATION | ECOLAB USA INC. (US) | 2012-09-13 | — | — | US | disclosed |
| US-7125827-B2 | Lubricant composition having a fatty acid, a polyalkylene glycol polymer, and an anionic surfactant, wherein the lubricant is for a conveyor system | ECOLAB INC. (US) | 2006-10-24 | — | — | US | disclosed |
| US-20040053793-A1 | Lubricant composition with reduced sensitivity to low pH for conveyor system | ECOLAB USA INC. | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11844349-B2 | Anti-microbial agent to control biomass accumulation in SO2 scrubbers | SPOUT1, FBL, SMURF1 | ESR1 3638/4885ESR2 3473/4885JAK2 3847/4885 |
| US-20180110224-A1 | ANTI-MICROBIAL AGENT TO CONTROL BIOMASS ACCUMULATION IN SO2 SCRUBBERS | SPOUT1, FBL, SMURF1 | ESR1 3638/4885ESR2 3473/4885JAK2 3847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.