Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23222053 | 0.82 | CYP1A2 (0.42) | CYP2D6CYP1A2KCNN4MAPK1KIF11 | |
| SCHEMBL11052947 | 0.80 | KCNN4 (0.46) | CYP2D6CYP1A2KCNN4MAPK1TAAR1 | |
| SCHEMBL6542251 | 0.79 | CYP2D6 (0.54) | CYP2D6CYP1A2KCNN4MAPK1TAAR1 | |
| SCHEMBL16033928 | 0.78 | MEN1 (0.46) | CYP2D6CYP1A2KCNN4MAPTKMT2A | |
| SCHEMBL999658 | 0.77 | CYP1A2 (0.52) | CYP2D6CYP1A2KCNN4MAPK1TAAR1 | |
| SCHEMBL7226298 | 0.77 | ALDH1A1 (0.40) | CYP2D6CYP1A2MAPK1MAPTKMT2A | |
| SCHEMBL3660630 | 0.76 | TAAR1 (0.48) | CYP2D6CYP1A2KCNN4MAPK1TAAR1 | |
| SCHEMBL3819639 | 0.75 | CYP1A2 (0.32) | CYP2D6CYP1A2 | |
| SCHEMBL9363854 | 0.75 | CYP2D6 (0.55) | CYP2D6CYP1A2KCNN4MAPK1TAAR1 | |
| SCHEMBL6470482 | 0.74 | CYP2C19 (0.55) | CYP2D6CYP1A2KCNN4MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11996557-B2 | Direct regeneration of lithium ion cathodes by ionothermal relithiation | UT-BATTELLE, LLC (US) | 2024-05-28 | — | — | US | disclosed |
| US-20220376240-A1 | DIRECT REGENERATION OF LITHIUM ION CATHODES BY IONOTHERMAL RELITHIATION | U. S. DEPARTMENT OF ENERGY | 2022-11-24 | — | — | US | disclosed |
| EP-3313396-B1 | G PROTEIN-COUPLED RECEPTOR KINASE INHIBITORS AND METHODS FOR USE OF THE SAME | UNIV MICHIGAN REGENTS (US) | 2021-12-15 | — | — | EP | disclosed |
| US-11186893-B2 | Rare earth amide compositions | UT-BATTELLE, LLC (US) | 2021-11-30 | — | — | US | disclosed |
| CN-111620914-B | Side-arm metallocene tetravalent transition metal complex containing neutral benzyl heteroatom ligand and application thereof | 吉林大学 | 2021-03-19 | — | — | CN | disclosed |
| US-20200370144-A1 | METHODS FOR LIQUID EXTRACTION OF RARE EARTH METALS USING IONIC LIQUIDS | UT-BATTELLE, LLC (US) | 2020-11-26 | — | — | US | disclosed |
| CN-111620914-A | Side-arm metallocene tetravalent transition metal complex containing neutral benzyl heteroatom ligand and application thereof | 吉林大学 | 2020-09-04 | — | — | CN | disclosed |
| US-10689727-B2 | Methods for liquid extraction of rare earth metals using ionic liquids | UT-BATTELLE, LLC (US) | 2020-06-23 | — | — | US | disclosed |
| US-10329283-B2 | G protein-coupled receptor kinase inhibitors and methods for use of the same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-06-25 | — | — | US | disclosed |
| US-20180186779-A1 | G PROTEIN-COUPLED RECEPTOR KINASE INHIBITORS AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2018-07-05 | — | — | US | disclosed |
| US-6372909-B1 | REACTING 3-PHENYLETHYL-2-PYRIDINECARBOXAMIDE WITH DEHYDRATING AGENT TO CYCLIZE AND FORM TRICYCLIC IMINE, HYDROLYZING TO FORM TRICYCLIC KETONE | SCHERING CORPORATION | 2002-04-16 | — | — | US | disclosed |
| EP-1131296-A2 | SYNTHESIS OF INTERMEDIATES USEFUL IN PREPARING TRICYCLIC COMPOUNDS | SCHERING CORPORATION (US) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000030589-A2 | SYNTHESIS OF INTERMEDIATES USEFUL IN PREPARING TRICYCLIC COMPOUNDS | SCHERING CORPORATION (US) | 2000-06-02 | — | — | WO | disclosed |
| EP-0196484-B1 | PRESSURE SENSITIVE MANIFOLD SHEET | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1990-05-09 | — | — | EP | disclosed |
| US-4704379-A | Pressure sensitive manifold sheet | KANZAKI PAPER MANUFACTURING CO. LTD. (JP) | 1987-11-03 | — | — | US | disclosed |
| EP-0196484-A1 | Pressure sensitive manifold sheet | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4559332-A | 20-Spiroxanes and analogues having an open ring E, processes for their manufacture, and pharmaceutical preparations thereof | CIBA GEIGY CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |
| EP-0003383-B1 | 4-AMINO-3-SULFONAMIDO PYRIDINE DERIVATIVES | A. CHRISTIAENS SOCIETE ANONYME (BE) | 1983-02-09 | — | — | EP | disclosed |
| EP-0003383-A2 | 4-Amino-3-sulfonamido pyridine derivatives | A. CHRISTIAENS SOCIETE ANONYME (BE) | 1979-08-08 | — | — | EP | disclosed |
| US-4069252-A | Process for the preparation of certain acyl cyanide compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329283-B2 | G protein-coupled receptor kinase inhibitors and methods for use of the same | GRK2, GRK4, GRK3 | CYP2D6 4363/4885CYP1A2 4352/4885KCNN4 1009/4885 |
| US-20180186779-A1 | G PROTEIN-COUPLED RECEPTOR KINASE INHIBITORS AND METHODS FOR USE OF THE SAME | GRK2, GRK4, GRK3 | CYP2D6 4363/4885CYP1A2 4352/4885KCNN4 1009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.