Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6736777 | 0.89 | ALDH1A1 (0.47) | CYP2C19ALDH1A1CYP2D6HSD17B10MEN1 | |
| SCHEMBL301345 | 0.86 | ALDH1A1 (0.57) | CYP2C19ALDH1A1CYP2D6HSD17B10MEN1 | |
| SCHEMBL6021075 | 0.86 | ALDH1A1 (0.57) | CYP2C19ALDH1A1CYP2D6HSD17B10MEN1 | |
| SCHEMBL13956903 | 0.84 | SRD5A2 (0.47) | CYP2C19ALDH1A1CYP2D6HSD17B10MEN1 | |
| SCHEMBL11624747 | 0.82 | KCNA5 (0.61) | CYP2C19CYP1A2CYP3A4CYP17A1KCNA5 | |
| SCHEMBL1153634 | 0.80 | CYP2D6 (0.52) | CYP2C19ALDH1A1CYP2D6HSD17B10MEN1 | |
| SCHEMBL17231876 | 0.80 | ALDH1A1 (0.52) | CYP2C19ALDH1A1CYP2D6HSD17B10MEN1 | |
| SCHEMBL2034432 | 0.80 | CYP2D6 (0.52) | CYP2C19ALDH1A1CYP2D6HSD17B10MEN1 | |
| SCHEMBL5696425 | 0.80 | ALDH1A1 (0.52) | CYP2C19ALDH1A1CYP2D6HSD17B10MEN1 | |
| SCHEMBL295338 | 0.80 | CYP2D6 (0.52) | CYP2C19ALDH1A1CYP2D6HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228504-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-11 | — | — | US | disclosed |
| US-20230371516-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC (US) | 2023-11-23 | — | — | US | disclosed |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2023-09-12 | — | — | US | disclosed |
| CN-108137478-B | Compound, composition thereof, purification method, resist pattern formation method, and amorphous film production method | 三菱瓦斯化学株式会社 | 2021-09-28 | — | — | CN | disclosed |
| CN-107924123-B | Material for lithography, method for producing same, composition for lithography, method for forming pattern, compound, resin, and method for purifying same | 学校法人关西大学 | 2021-08-06 | — | — | CN | disclosed |
| CN-107428717-B | Resist composition, resist pattern forming method, and polyphenol compound used for same | 三菱瓦斯化学株式会社 | 2021-04-23 | — | — | CN | disclosed |
| CN-107533290-B | Resist base material, resist composition, and method for forming resist pattern | 三菱瓦斯化学株式会社 | 2021-04-09 | — | — | CN | disclosed |
| US-10597353-B2 | Processes for the preparation of diastereomerically and enantiomerically enriched oxazolines | Química Sintética, S.A. (ES) | 2020-03-24 | — | — | US | disclosed |
| US-20180133212-A1 | COMBINATION OF A BCL-2 INHIBITOR AND A BROMODOMAIN INHIBITOR FOR TREATING CANCER | GILEAD SCIENCES, INC. | 2018-05-17 | — | — | US | disclosed |
| US-20170295792-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2017-10-19 | — | — | US | disclosed |
| US-20110260343-A1 | POLYMERIC COMPOSITIONS COMPRISING PER(PHENYLETHYNYL) ARENE DERIVATIVES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2011-10-27 | — | — | US | disclosed |
| US-20100324295-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED 5-QUINOLYL-OXAZOLES AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | SCHERING CORPORATION | 2010-12-23 | — | — | US | disclosed |
| US-20100324295-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED 5-QUINOLYL-OXAZOLES AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | SCHERING CORPORATION | 2010-12-23 | — | — | US | disclosed |
| WO-2010019488-A1 | POLYMERIC COMPOSITIONS COMPRISING PER(PHENYLETHYNYL) ARENE DERIVATIVES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2010-02-18 | — | — | WO | disclosed |
| US-7511062-B2 | Substituted 2-quinolyl-oxazoles useful as PDE4 inhibitors | SCHERING CORPORATION (US) | 2009-03-31 | — | — | US | disclosed |
| US-20070249586-A1 | Benzothiazole derivatives having beta-2-adrenoreceptor agonist activity | CUENOUD BERNARD | 2007-10-25 | — | — | US | disclosed |
| US-20070249586-A1 | Benzothiazole derivatives having beta-2-adrenoreceptor agonist activity | CUENOUD BERNARD | 2007-10-25 | — | — | US | disclosed |
| US-20070232813-A1 | Substituted Cyclohexadienals - Syntheses and Applications | THE TEXAS A&M UNIVERSITY SYSTEM | 2007-10-04 | — | — | US | disclosed |
| CN-1798736-A | Novel quinoline, tetrahydroquinazoline and pyrimidine derivatives and methods of treatment related to their use | ARENA PHARM INC (JP) | 2006-07-05 | — | — | CN | disclosed |
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | TAISHO PHARMACEUTICAL CO., LTD. | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232813-A1 | Substituted Cyclohexadienals - Syntheses and Applications | DHPS, COASY, PPIE | CYP2C19 1807/4885ALDH1A1 351/4885CYP2D6 986/4885 |
| US-20180133212-A1 | COMBINATION OF A BCL-2 INHIBITOR AND A BROMODOMAIN INHIBITOR FOR TREATING CANCER | BCL2, BAK1, BRD4 | CYP2C19 4696/4885ALDH1A1 4196/4885CYP2D6 4691/4885 |
| US-20170295792-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | PFAS, FKBP2, FKBP14 | CYP2C19 117/4885ALDH1A1 1160/4885CYP2D6 55/4885 |
| US-20100324295-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED 5-QUINOLYL-OXAZOLES AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | PDE4B, PDE4A, PDE3B | CYP2C19 27/4885ALDH1A1 332/4885CYP2D6 73/4885 |
| US-20070249586-A1 | Benzothiazole derivatives having beta-2-adrenoreceptor agonist activity | ADRB2, ADRB1, ADRA2C | CYP2C19 1579/4885ALDH1A1 829/4885CYP2D6 1199/4885 |
| US-20240228504-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | SLC10A1, NR1H4, SLC10A2 | CYP2C19 439/4885ALDH1A1 3140/4885CYP2D6 55/4885 |
| US-20230371516-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | CYP2C19 92/4885ALDH1A1 1350/4885CYP2D6 61/4885 |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | CYP2C19 92/4885ALDH1A1 1350/4885CYP2D6 61/4885 |
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | HCRTR2, MCHR1, MCHR2 | CYP2C19 232/4885ALDH1A1 2036/4885CYP2D6 653/4885 |
| US-10597353-B2 | Processes for the preparation of diastereomerically and enantiomerically enriched oxazolines | HPD, HAAO, CYP8B1 | CYP2C19 92/4885ALDH1A1 126/4885CYP2D6 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.