SCHEMBL6085477

SCHEMBL6085477

CC(=O)N(CC(C)C)C1CCS(=O)(=O)c2sc(S(=O)(=O)O)cc21

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA2 P00918 20/20 0.50
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6085929 0.92 CA2 (0.50) CA2CA1
SCHEMBL6086275 0.91 CA2 (0.63) CA2CA1
SCHEMBL6085743 0.77 GAA (0.43) CA2
SCHEMBL6085860 0.70 CA2 (0.66) CA2CA1
Hydrochloric Acid SCHEMBL10514436 0.66 CA2 (0.76) CA2
SCHEMBL6087724 0.66 GAA (0.42) CA2
Sezolamide SCHEMBL6086814 0.63 CA2 (1.00) CA2CA1
Sezolamide SCHEMBL637480 0.63 CA2 (1.00) CA2CA1
Sezolamide SCHEMBL6085905 0.62 CA2 (1.00) CA2
SCHEMBL10515039 0.62 CA2 (0.69) CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7030250-B2 Process for obtaining 4-(N-alkylamino)-5,6-dihydro-4H-thien-(2,3-b)-thiopyran-2-sulfonamide-7,7-dioxides and intermediates RAGATIVES, S.L. (ES) 2006-04-18 US claimed
EP-1329453-B1 METHOD FOR OBTAINING 4-(N-ALKYLAMINE)-5, 6-DIHYDRO-4H-THIENO-(2,3-B)-THIOPYRAN-2-SULFONAMIDE-7, 7-DIOXIDES AND INTERMEDIATE PRODUCTS RAGACTIVES SL (ES) 2004-06-16 EP claimed
US-20030220509-A1 Process for obtaining 4-(N-alkylamino)-5,6-dihydro-4H-thien-(2,3-b)-thiopyran-2-sulfonamide-7,7-dioxides and intermediates RAGACTIVES, S.L. 2003-11-27 US claimed
EP-1329453-A1 METHOD FOR OBTAINING 4-(N-ALKYLAMINE)-5, 6-DIHYDRO-4H-THIENO-(2,3-B)-THIOPYRAN-2-SULFAMIDE-7, 7-DIOXIDES AND INTERMEDIATE PRODUCTS Ragactives, S.L. (ES) 2003-07-23 EP claimed
US-7030250-B2 Process for obtaining 4-(N-alkylamino)-5,6-dihydro-4H-thien-(2,3-b)-thiopyran-2-sulfonamide-7,7-dioxides and intermediates RAGATIVES, S.L. (ES) 2006-04-18 US disclosed
EP-1329453-B1 METHOD FOR OBTAINING 4-(N-ALKYLAMINE)-5, 6-DIHYDRO-4H-THIENO-(2,3-B)-THIOPYRAN-2-SULFONAMIDE-7, 7-DIOXIDES AND INTERMEDIATE PRODUCTS RAGACTIVES SL (ES) 2004-06-16 EP disclosed
US-20030220509-A1 Process for obtaining 4-(N-alkylamino)-5,6-dihydro-4H-thien-(2,3-b)-thiopyran-2-sulfonamide-7,7-dioxides and intermediates RAGACTIVES, S.L. 2003-11-27 US disclosed
EP-1329453-A1 METHOD FOR OBTAINING 4-(N-ALKYLAMINE)-5, 6-DIHYDRO-4H-THIENO-(2,3-B)-THIOPYRAN-2-SULFAMIDE-7, 7-DIOXIDES AND INTERMEDIATE PRODUCTS Ragactives, S.L. (ES) 2003-07-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030220509-A1 Process for obtaining 4-(N-alkylamino)-5,6-dihydro-4H-thien-(2,3-b)-thiopyran-2-sulfonamide-7,7-dioxides and intermediates CA7, CA2, CA4 CA2 2/4885CA1 24/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.