Sezolamide

Sezolamide

SCHEMBL637480

CC(C)CN[C@H]1CCS(=O)(=O)c2sc(S(N)(=O)=O)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 20/20 1.00
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA3 P07451 1/20 0.55
AR P10275 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA13 Q8N1Q1 1/20 0.55
CA14 Q9ULX7 1/20 0.55
CA5B Q9Y2D0 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sezolamide SCHEMBL6086814 1.00 CA2 (1.00) CA2CA12CA1CA3AR
Sezolamide SCHEMBL9879354 1.00 CA2 (1.00) CA2CA12CA1CA3AR
Sezolamide SCHEMBL668227 0.99 CA2 (1.00) CA2
Sezolamide SCHEMBL6085905 0.99 CA2 (1.00) CA2
Sezolamide SCHEMBL8128967 0.98 CA2 (0.98) CA2
SCHEMBL9205397 0.92 CA2 (0.85) CA2CA12CA1CA3AR
SCHEMBL19826857 0.89 CA2 (1.00) CA2CA12CA1CA3AR
SCHEMBL10513416 0.89 CA2 (1.00) CA2CA12CA1CA3AR
Hydrochloric Acid SCHEMBL10513807 0.85 CA2 (1.00) CA2
SCHEMBL10514131 0.84 CA2 (1.00) CA2CA12CA1CA3AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 557 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724079-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2026-04-15 EP claimed
US-20260048096-A1 METHODS AND COMPOSITIONS FOR PRESERVING THE RETINAL OUTER NUCLEAR LAYER (ONL), PHOTORECEPTORS, AND RETINAL THICKNESS STEALTH BIOTHERAPEUTICS INC. (US) 2026-02-19 US claimed
EP-4596049-A2 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2025-08-06 EP claimed
EP-4302829-B1 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION STEALTH BIOTHERAPEUTICS INC (US) 2025-05-21 EP claimed
US-20250090621-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION STEALTH BIOTHERAPEUTICS INC. (US) 2025-03-20 US claimed
WO-2024254164-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION STEALTH BIOTHERAPEUTICS INC. (US) 2024-12-12 WO claimed
US-20240350577-A1 METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING DOMINANT OPTIC ATROPHY STEALTH BIOTHERAPEUTICS INC. (US) 2024-10-24 US claimed
EP-4419123-A1 METHODS AND COMPOSITIONS COMPRISING PEPTIDOMIMITICS FOR TREATING, PREVENTING, INHIBITING, AMELIORATING OR DELAYING THE ONSET OF OPHTHALMIC CONDITIONS Stealth BioTherapeutics Inc. (US) 2024-08-28 EP claimed
US-11944662-B2 Methods and compositions for preventing or treating ophthalmic conditions STEALTH BIOTHERAPEUTICS INC. (US) 2024-04-02 US claimed
US-20240024408-A1 METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING LEBER'S HEREDITARY OPTIC NEUROPATHY STEALTH BIOTHERAPEUTICS INC. (US) 2024-01-25 US claimed
US-20060177430-A1 Treatment of ocular disorders with ophthalmic formulations containing methylsulfonylmethane as a transport enhancer CHAKSHU RESEARCH INC (US) 2006-08-10 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20040013609-A1 For identification of substances for treatment or prevention of insufficient longitudinal growth of eye(hypermetropia) or excessive longitudinal growth of eye(myopia); involves measurement of effect on retinal pigment epithelium TRIER KLAUS (DK) 2004-01-22 US claimed
EP-1112056-B1 ANTIPERSPIRANT PRODUCT AND METHOD UNILEVER PLC (GB) 2003-01-02 EP claimed
EP-1112056-A1 ANTIPERSPIRANT PRODUCT AND METHOD UNILEVER PLC (GB) 2001-07-04 EP claimed
US-6251376-B1 NEUTRALIZATION FOR SKINS ELEVATION OF PH OF SWEAT UNILEVER HOME & PERSONAL CARE USA 2001-06-26 US claimed
WO-2000015185-A1 ANTIPERSPIRANT PRODUCT AND METHOD UNILEVER PLC (GB) 2000-03-23 WO claimed
WO-1998030900-A2 SCREENING METHOD FOR COMPOUNDS ACTIVE IN TREATING MYOPIA AND HYPERMETROPIA KLAUS TRIER APS (DK) 1998-07-16 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240024408-A1 METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING LEBER'S HEREDITARY OPTIC NEUROPATHY CLN6, PRPH, TSG101 CA2 1462/4885CA12 2983/4885CA1 3800/4885
US-11944662-B2 Methods and compositions for preventing or treating ophthalmic conditions CRYAA, CRYAB, IAPP CA2 221/4885CA12 1247/4885CA1 2222/4885
US-20260048096-A1 METHODS AND COMPOSITIONS FOR PRESERVING THE RETINAL OUTER NUCLEAR LAYER (ONL), PHOTORECEPTORS, AND RETINAL THICKNESS NR2E3, ALDH1A2, PDE6D CA2 197/4885CA12 2963/4885CA1 2626/4885
US-20250090621-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION PDE6C, PDE6A, PDE6B CA2 1474/4885CA12 1970/4885CA1 3132/4885
US-20040013609-A1 For identification of substances for treatment or prevention of insufficient longitudinal growth of eye(hypermetropia) or excessive longitudinal growth of eye(myopia); involves measurement of effect on retinal pigment epithelium RYR1, ATP2A2, ATP2A1 CA2 39/4885CA12 876/4885CA1 1185/4885
US-20240350577-A1 METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING DOMINANT OPTIC ATROPHY CRYAA, CRYAB, PRPH CA2 1274/4885CA12 3224/4885CA1 2618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.