Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.32 |
| ▸ | CTSD | P07339 | 2/20 | 0.32 |
| ▸ | CTSE | P14091 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849258 | 0.92 | GRIN1 (0.32) | GRIN1GRIN2BHDAC1HDAC8HDAC6 | |
| SCHEMBL6088109 | 0.92 | KMT2A (0.37) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL10204389 | 0.90 | PGR (0.33) | GRIN1GRIN2BHDAC1HDAC8HDAC6 | |
| SCHEMBL501413 | 0.89 | KMT2A (0.35) | GRIN1GRIN2BHDAC1HDAC8HDAC6 | |
| SCHEMBL10204282 | 0.88 | KMT2A (0.36) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL6085624 | 0.87 | TYMS (0.36) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL6086806 | 0.87 | KMT2A (0.34) | HDAC8HDAC6MEN1KMT2ATDP1 | |
| SCHEMBL6089258 | 0.87 | KMT2A (0.41) | MEN1KMT2A | |
| SCHEMBL10204696 | 0.86 | MEN1 (0.34) | GRIN1GRIN2BMEN1KMT2ATDP1 | |
| SCHEMBL6086542 | 0.86 | HDAC1 (0.38) | GRIN1GRIN2BHDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |