Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21524526 | 1.00 | LMNA (0.58) | LMNATRPA1ADRA2CKDM4EADRA2A | |
| SCHEMBL7692329 | 0.84 | TAAR1 (0.56) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL10581707 | 0.84 | TAAR1 (0.56) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL14402480 | 0.83 | AOC3 (0.50) | LMNATRPA1ADRA2CKDM4EADRA2A | |
| SCHEMBL13849318 | 0.83 | AOC3 (0.50) | LMNATRPA1ADRA2CKDM4EADRA2A | |
| SCHEMBL14402548 | 0.83 | AOC3 (0.50) | LMNATRPA1ADRA2CKDM4EADRA2A | |
| SCHEMBL20738581 | 0.83 | AOC3 (0.50) | LMNATRPA1ADRA2CKDM4EADRA2A | |
| SCHEMBL17086739 | 0.82 | TRPA1 (0.50) | LMNATRPA1ADRA2CKDM4EADRA2A | |
| SCHEMBL17086745 | 0.82 | TRPA1 (0.50) | LMNATRPA1ADRA2CKDM4EADRA2A | |
| SCHEMBL17086740 | 0.82 | TRPA1 (0.50) | LMNATRPA1ADRA2CKDM4EADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111163761-A | Targeted drugs related to trimethylamine and/or trimethylamine-N-oxide | 普梭梅根公司 | 2020-05-15 | — | — | CN | disclosed |
| US-20170266167-A1 | ERK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-09-21 | — | — | US | disclosed |
| US-8399398-B2 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-8399398-B2 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-8399398-B2 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-20120041077-A1 | ORGANOLEPTIC COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2012-02-16 | — | — | US | disclosed |
| US-20120041077-A1 | ORGANOLEPTIC COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2012-02-16 | — | — | US | disclosed |
| US-20120041077-A1 | ORGANOLEPTIC COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2012-02-16 | — | — | US | disclosed |
| US-8071530-B2 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071530-B2 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-12-06 | — | — | US | disclosed |
| US-20080039361-A1 | Organoleptic Compounds and Their Use In Perfume Compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2008-02-14 | — | — | US | disclosed |
| US-20080039361-A1 | Organoleptic Compounds and Their Use In Perfume Compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2008-02-14 | — | — | US | disclosed |
| EP-1847533-A1 | SIX-MEMBERED HETEROCYCLIC COMPOUND AND THE USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2007-10-24 | — | — | EP | disclosed |
| EP-1301288-B1 | CLEANING SHEET, CONVEYING MEMBER USING THE SAME, AND SUBSTRATE PROCESSING EQUIPMENT CLEANING METHOD USING THEM | NITTO DENKO CORP (JP) | 2006-11-08 | — | — | EP | disclosed |
| US-6821620-B2 | CUTTING CLEANING SHEET; THEN CURING; SEMICONDUCTORS | NITTO DENKO CORPORATION (JP) | 2004-11-23 | — | — | US | disclosed |
| US-20030180532-A1 | Cleaning sheet , conveying member using the same, and substrate processing equipment cleaning method using them | NITTO DENKO CORPORATION (JP) | 2003-09-25 | — | — | US | disclosed |
| EP-1301288-A1 | CLEANING SHEET, CONVEYING MEMBER USING THE SAME, AND SUBSTRATE PROCESSING EQUIPMENT CLEANING METHOD USING THEM | NITTO DENKO CORPORATION (JP) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002005975-A1 | CLEANING SHEET, CONVEYING MEMBER USING THE SAME, AND SUBSTRATE PROCESSING EQUIPMENT CLEANING METHOD USING THEM | NITTO DENKO CORPORATION (JP) | 2002-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170266167-A1 | ERK INHIBITORS | MAPK1, MAPK3, MAPK6 | LMNA 4756/4885TRPA1 3699/4885ADRA2C 2053/4885 |
| US-20120041077-A1 | ORGANOLEPTIC COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | TRPA1, TRPV1, OR51E2 | LMNA 3299/4885TRPA1 1/4885ADRA2C 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.