Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1607866 | 0.83 | TP53 (0.55) | SMN1; SMN2CYP3A4GAALMNAMAPT | |
| SCHEMBL940807 | 0.83 | TP53 (0.55) | SMN1; SMN2CYP3A4GAALMNAMAPT | |
| Hydrochloric Acid SCHEMBL11722776 | 0.81 | TP53 (0.53) | SMN1; SMN2CYP3A4GAALMNAMAPT | |
| Hydrochloric Acid SCHEMBL11722772 | 0.81 | TP53 (0.53) | SMN1; SMN2CYP3A4GAALMNAMAPT | |
| SCHEMBL287220 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2CYP3A4GAALMNAMAPT | |
| SCHEMBL11722198 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2CYP3A4TSHRGAAMAPT | |
| SCHEMBL11719928 | 0.80 | KMT2A (0.51) | SMN1; SMN2CYP3A4GAAMAPTKMT2A | |
| SCHEMBL11725136 | 0.79 | MAPT (0.54) | SMN1; SMN2CYP3A4GAAMAPTKMT2A | |
| SCHEMBL15129079 | 0.78 | CA1 (0.49) | SMN1; SMN2CYP3A4GAAMAPTKMT2A | |
| Nitromide SCHEMBL193674 | 0.78 | CYP3A4 (1.00) | SMN1; SMN2CYP3A4TSHRGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053608-A | 3-NITROPYRIDINE CARBOXAMIDES, POULTRY FEED | SANKYO COMPANY LIMITED (JA) | 1977-10-11 | — | — | US | claimed |
| WO-2022247743-A1 | COMPOUNDS AND THEIR USE AS VACCINE ADJUVANTS | FULGENT GENETICS, INC. (US) | 2022-12-01 | — | — | WO | disclosed |
| WO-2022246597-A1 | IMIDAZOPYRIDINE DERIVATIVES AS STING AGONISTS | FOREVER MILLETS LIMITED (CN) | 2022-12-01 | — | — | WO | disclosed |
| CN-114585623-A | Bis [ N- ((5-carbamoyl) -1H-benzo [ d ] imidazol-2-yl) pyrazole-5-carboxamide ] derivatives and related compounds as STING (interferon gene stimulator) agonists for the treatment of cancer | 梅尔莎纳医疗公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-104245698-A | Nitrogen-containing heterocyclic compound | TAKEDA PHARMACEUTICAL | 2014-12-24 | — | — | CN | disclosed |
| CN-101652353-A | 3-hydrogen quinazoline-4-one derivatives as stearoyl coa desaturase inhibitors | CV THERAPEUTICS INC US | 2010-02-17 | — | — | CN | disclosed |
| US-7067552-B2 | Radiosensitizing taxanes and their pharmaceutical preparations | FLORIDA STATE UNIVERSITY (US) | 2006-06-27 | — | — | US | disclosed |
| US-20020040155-A1 | Radiosensitizing taxanes and their pharmaceutical preparations | FLORIDA STATE UNIVERSITY | 2002-04-04 | — | — | US | disclosed |
| EP-0956016-A4 | PHARMACEUTICAL COMPOUNDS COMPRISING POLYAMINES SUBSTITUTED WITH ELECTRON-AFFINIC GROUPS | UNIV FLORIDA STATE (US) | 2001-11-14 | — | — | EP | disclosed |
| US-6255495-B1 | KILLING HYPOXIC TUMOR CELLS AND TREATING DERMATOLOGICAL DISEASES IN WARM-BLOODED ANIMALS VIA ADMINISTERING RADIOSENSITIZING AMOUNT OF ELECTRON-AFFINIC-DIAMINE | FLORIDA STATE UNIVERSITY | 2001-07-03 | — | — | US | disclosed |
| US-6057453-A | OXIDATION, FORMING RADIOSENSITIZING DIAMINES, REDUCTION | FLORIDA STATE UNIVERSITY (US) | 2000-05-02 | — | — | US | disclosed |
| EP-0956016-A1 | PHARMACEUTICAL COMPOUNDS COMPRISING POLYAMINES SUBSTITUTED WITH ELECTRON-AFFINIC GROUPS | Florida State University (US) | 1999-11-17 | — | — | EP | disclosed |
| CN-1232395-A | Pharmaceutical compounds containing polyamines substituted with electron affinity groups | UNIV FLORIDA STATE (US) | 1999-10-20 | — | — | CN | disclosed |
| CN-1211919-A | Radiosensitizing taxanes and their pharmaceutical preparations | UNIV FLORIDA STATE (US) | 1999-03-24 | — | — | CN | disclosed |
| EP-0855909-A1 | RADIOSENSITIZING TAXANES AND THEIR PHARMACEUTICAL PREPARATIONS | FLORIDA STATE UNIVERSITY (US) | 1998-08-05 | — | — | EP | disclosed |
| WO-1998014190-A9 | PHARMACEUTICAL COMPOUNDS COMPRISING POLYAMINES SUBSTITUTED WITH ELECTRON-AFFINIC GROUPS | — | 1998-07-30 | — | — | WO | disclosed |
| WO-1998014190-A1 | PHARMACEUTICAL COMPOUNDS COMPRISING POLYAMINES SUBSTITUTED WITH ELECTRON-AFFINIC GROUPS | FLORIDA STATE UNIVERSITY (US) | 1998-04-09 | — | — | WO | disclosed |
| WO-1997009979-A9 | RADIOSENSITIZING TAXANES AND THEIR PHARMACEUTICAL PREPARATIONS | — | 1997-06-05 | — | — | WO | disclosed |
| WO-1997009979-A1 | RADIOSENSITIZING TAXANES AND THEIR PHARMACEUTICAL PREPARATIONS | FLORIDA STATE UNIVERSITY (US) | 1997-03-20 | — | — | WO | disclosed |
| US-4053608-A | 3-NITROPYRIDINE CARBOXAMIDES, POULTRY FEED | SANKYO COMPANY LIMITED (JA) | 1977-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040155-A1 | Radiosensitizing taxanes and their pharmaceutical preparations | TOP2A, XPA, TP53 | SMN1; SMN2 1100/4885CYP3A4 2600/4885TSHR 3058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.