Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13562166 | 0.71 | TP53 (0.32) | — | |
| SCHEMBL4212579 | 0.71 | RXRA (0.36) | — | |
| SCHEMBL12871708 | 0.71 | ELANE (0.36) | ELANE | |
| SCHEMBL12267885 | 0.70 | MAPT (0.45) | — | |
| SCHEMBL19846937 | 0.70 | TP53 (0.31) | — | |
| SCHEMBL10881461 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL1912779 | 0.70 | BRD4 (0.32) | — | |
| SCHEMBL16201624 | 0.69 | CDC25A (0.32) | — | |
| SCHEMBL12633924 | 0.69 | — | — | |
| SCHEMBL7923923 | 0.65 | EGFR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1741428-A2 | Cell adhesion inhibitors | Biogen Idec MA, Inc. (US) | 2007-01-10 | — | — | EP | disclosed |
| US-6982260-B1 | Quinazolines and their use for inhibiting cyclin-dependent kinase enzymes | WARNER-LAMBERT COMPANY (US) | 2006-01-03 | — | — | US | disclosed |
| EP-1235815-A1 | QUINAZOLINES AND THEIR USE FOR INHIBITING CYCLIN-DEPENDENT KINASE ENZYMES | WARNER-LAMBERT COMPANY (US) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038315-A1 | QUINAZOLINES AND THEIR USE FOR INHIBITING CYCLIN-DEPENDENT KINASE ENZYMES | WARNER-LAMBERT COMPANY (US) | 2001-05-31 | — | — | WO | disclosed |