Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12829055 | 0.85 | MAOB (0.36) | MEN1KMT2ATDP1PDE3BPDE3A | |
| SCHEMBL6087128 | 0.83 | TPH1 (0.34) | MEN1KMT2AHTTGRIN1GRIN2B | |
| SCHEMBL6087042 | 0.83 | SMN1; SMN2 (0.36) | MEN1KMT2ATDP1GRIN1GRIN2B | |
| SCHEMBL8067201 | 0.82 | MEN1 (0.35) | MEN1KMT2ATDP1HTT | |
| SCHEMBL7847745 | 0.81 | ELANE (0.32) | MEN1KMT2AGRIN1GRIN2BCYP1A2 | |
| SCHEMBL8069285 | 0.81 | ALDH1A1 (0.34) | MEN1KMT2ATDP1PDE3BPDE3A | |
| SCHEMBL6087870 | 0.81 | SMN1; SMN2 (0.38) | MEN1KMT2AHTTCYP2C19SMN1; SMN2 | |
| SCHEMBL1484944 | 0.81 | PDE3B (0.31) | PDE3BPDE3A | |
| SCHEMBL8067216 | 0.81 | PNP (0.36) | HTT | |
| SCHEMBL6086817 | 0.80 | HPGD (0.43) | MEN1KMT2AHTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |