Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.31 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12752168 | 0.89 | KMT2A (0.40) | KMT2AMEN1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6089500 | 0.86 | TPH1 (0.38) | KMT2AMEN1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7758274 | 0.85 | TPH1 (0.37) | KMT2AMEN1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7753931 | 0.84 | KMT2A (0.37) | KMT2AMEN1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7758821 | 0.84 | KMT2A (0.37) | KMT2AMEN1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7031964 | 0.84 | KMT2A (0.39) | KMT2AMEN1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6087554 | 0.84 | ALDH1A1 (0.40) | KMT2AMEN1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6088185 | 0.84 | KMT2A (0.37) | KMT2AMEN1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7757663 | 0.83 | KMT2A (0.36) | KMT2AMEN1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6087020 | 0.83 | GRIN1 (0.43) | KMT2AMEN1TDP1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |