Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 9/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088338 | 0.87 | TYMS (0.44) | TYMSP2RX3PPARGPPARAGRIN2B | |
| SCHEMBL6634103 | 0.85 | KMT2A (0.38) | MEN1ALDH1A1KMT2A | |
| SCHEMBL7846719 | 0.85 | TYMS (0.41) | TYMSP2RX3PPARGPPARACYP2C9 | |
| SCHEMBL6089258 | 0.85 | KMT2A (0.41) | CYP2C9MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL6088109 | 0.84 | KMT2A (0.37) | CYP2C9HDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL6086464 | 0.82 | DAO (0.44) | CYP2C9MEN1ALDH1A1KMT2A | |
| SCHEMBL6086542 | 0.82 | HDAC1 (0.38) | CYP2C9GRIN2BHDAC1HDAC8HDAC6 | |
| SCHEMBL6637345 | 0.82 | GAA (0.39) | TYMSCYP2C9MEN1MAPTKMT2A | |
| SCHEMBL6087425 | 0.82 | TYMS (0.45) | TYMSP2RX3GRIN2BHCRTR1HCRTR2 | |
| SCHEMBL6087598 | 0.81 | MEN1 (0.37) | MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |