Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086817 | 0.86 | HPGD (0.43) | ALDH1A1TSHRMEN1MAPTKMT2A | |
| SCHEMBL6087128 | 0.85 | TPH1 (0.34) | GRIN2BALDH1A1TSHRMEN1MAPT | |
| SCHEMBL6086972 | 0.85 | TYMS (0.46) | TYMSGRM2GRIN2BHCRTR1HCRTR2 | |
| SCHEMBL6086296 | 0.84 | TSHR (0.34) | GRIN2BALDH1A1TSHRMEN1MAPT | |
| SCHEMBL6087068 | 0.82 | DAO (0.46) | ALDH1A1TSHRMEN1MAPTKMT2A | |
| SCHEMBL6086749 | 0.82 | TYMS (0.43) | TYMSGRM2GRIN2BP2RX3HCRTR1 | |
| SCHEMBL6086491 | 0.82 | PDE5A (0.33) | P2RX3ALDH1A1TSHRMEN1MAPT | |
| SCHEMBL6088310 | 0.82 | GRIN1 (0.36) | GRIN2BALDH1A1KMT2ADAO | |
| SCHEMBL6087976 | 0.82 | TYMS (0.43) | TYMSGRIN2BP2RX3HCRTR1HCRTR2 | |
| SCHEMBL501608 | 0.81 | GRIN1 (0.33) | GRIN2BP2RX3ALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |