⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2067414 | 0.76 | TP53 (0.32) | — | |
| SCHEMBL4757736 | 0.66 | MET (0.34) | — | |
| SCHEMBL3931082 | 0.65 | — | — | |
| SCHEMBL34349 | 0.64 | POLB (0.48) | — | |
| SCHEMBL3943448 | 0.63 | — | — | |
| SCHEMBL3934683 | 0.58 | — | — | |
| SCHEMBL4059857 | 0.58 | — | — | |
| SCHEMBL2067745 | 0.56 | — | — | |
| SCHEMBL1190711 | 0.54 | — | — | |
| SCHEMBL165149 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154724-A2 | PROCESSES AND COMPOUNDS FOR PREPARING SPIROLIGOMERS | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-08-17 | — | — | WO | claimed |
| US-9695189-B2 | Chemical crosslinkers and compositions thereof | Nguyen, Mark Quang (US) | 2017-07-04 | — | — | US | claimed |
| US-20140249319-A1 | CHEMICAL CROSSLINKERS AND COMPOSITIONS THEREOF | Nguyen, Mark Quang (US) | 2014-09-04 | — | — | US | claimed |
| WO-2023154724-A2 | PROCESSES AND COMPOUNDS FOR PREPARING SPIROLIGOMERS | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-08-17 | — | — | WO | disclosed |
| US-11111335-B2 | Method of preparing carboxylic acid functionalized polymers | NEKTAR THERAPEUTICS (US) | 2021-09-07 | — | — | US | disclosed |
| EP-1756173-B1 | METHOD OF PREPARING PROPIONIC ACID-TERMINATED POLYMERS | NEKTAR THERAPEUTICS (US) | 2019-04-03 | — | — | EP | disclosed |
| US-20180282476-A1 | METHOD OF PREPARING CARBOXYLIC ACID FUNCTIONALIZED POLYMERS | NEKTAR THERAPEUTICS | 2018-10-04 | — | — | US | disclosed |
| US-10011682-B2 | Method of preparing carboxylic acid functionalized polymers | NEKTAR THERAPEUTICS (US) | 2018-07-03 | — | — | US | disclosed |
| US-9695189-B2 | Chemical crosslinkers and compositions thereof | Nguyen, Mark Quang (US) | 2017-07-04 | — | — | US | disclosed |
| EP-2812346-A1 | LIGANDS FOR ANTIBODY AND FC-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMOTOGRAPHY IV | Graffinity Pharmaceuticals GmbH (DE) | 2014-12-17 | — | — | EP | disclosed |
| US-20140249319-A1 | CHEMICAL CROSSLINKERS AND COMPOSITIONS THEREOF | Nguyen, Mark Quang (US) | 2014-09-04 | — | — | US | disclosed |
| EP-1692206-B1 | METHOD OF PREPARING CARBOXYLIC ACID FUNCTIONALIZED POLYMERS | NEKTAR THERAPEUTICS (US) | 2010-04-21 | — | — | EP | disclosed |
| US-20100004428-A1 | Method of Preparing Propionic Acid-Terminated Polymers | NEKTAR THERAPEUTICS (US) | 2010-01-07 | — | — | US | disclosed |
| US-7608663-B2 | reacting a water soluble and non-peptidic polymer comprising at least one hydroxyl group with a tertiary alkyl acrylate in the presence of a catalyst to form a propionic acid ester of the polymer; acid treatment; may be further derivatized; particularly propionic acid-terminated poly(ethylene glycol)s | NEKTAR THERAPEUTICS (US) | 2009-10-27 | — | — | US | disclosed |
| EP-1756173-A2 | METHOD OF PREPARING PROPIONIC ACID-TERMINATED POLYMERS | Nektar Therapeutics Al, Corporation (US) | 2007-02-28 | — | — | EP | disclosed |
| EP-1692206-A1 | METHOD OF PREPARING CARBOXYLIC ACID FUNCTIONALIZED POLYMERS | Nektar Therapeutics Al, Corporation (US) | 2006-08-23 | — | — | EP | disclosed |
| US-20050214250-A1 | Method of preparing carboxylic acid functionalized polymers | NEKTAR THERAPEUTICS | 2005-09-29 | — | — | US | disclosed |
| US-20050171291-A1 | Method of preparing propionic acid-terminated polymers | NEKTAR THERAPEUTICS | 2005-08-04 | — | — | US | disclosed |
| WO-2005070973-A2 | METHOD OF PREPARING PROPIONIC ACID-TERMINATED POLYMERS | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2005-08-04 | — | — | WO | disclosed |
| WO-2005047366-A1 | METHOD OF PREPARING CARBOXYLIC ACID FUNCTIONALIZED POLYMERS | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2005-05-26 | — | — | WO | disclosed |